Gene Expression and Molecular Cloning Products & Reviews

Modulation of gene expression with modified oligos

FDA approved Modern cellular and molecular biology poses the strictest requirements for the usage of sensitive samples such as living cells, nucleic acids or other cell components. With this ambition of quality in mind, Eppendorf offers a large selection of microcapillaries for the most varied applications. VacuTips capillaries and TransferTips® for intracytoplasmatic sperm injection (ICSI ) TransferTip (ES) for embryo…

Unleash the full power of a well-designed library. With Twist Bioscience, you are assured that the library you design contains the specific modifications, exactly where you want them, saving you valuable resources for the downstream screening process.

BioIVT is the leading provider of quality, highly characterized, ethically procured ADME research products, featuring custom preparation or extensive ready-to-ship inventory, large lot sizes and expert support.

CRISPR off-target effect may result in anomalous insertions, deletions and translocation. It is critical to have a sensitive detection tool for the off-target editing. Based on the highly sensitive, accurate and stable TargetSeq® hybridization capture sequencing technology and MultipSeq® multiplex amplicon sequencing technology, iGeneTech provides a new, fast and cost-effective solution for CRISPR off-target validation to dete…

Type VI-S, lyophilized powder, for diagnostic assay manufacturing

Type I-S, 65-85% protein (≥75% of protein is clottable)

1,6-α-D-Glucan 6-glucanohydrolase

Recombinant, expressed in Pichia pastoris, ATPase ≥1000 units/mg protein, lyophilized powder.

Fast-track your route to a modernized workflow with the only in vitro bioavailability assessment tool on the market

Creative Biolabs delivers an end-to-end CAR-T development pathway—from target/scFv discovery, CAR design and vectoring, and cell engineering to in-vitro/in-vivo efficacy, IND authoring, and manufacturing support. Modular and GMP-aligned, the platform spans autologous and allogeneic routes (incl. TRAC/Cas9 and mRNA) to de-risk translation for hematologic and solid tumor programs.

End‑to‑end TCR‑like antibody services targeting peptide–MHC complexes—covering immunogen design, pMHC screening, affinity maturation, developability optimization, and functional validation—with output as IgG, bispecifics, or CAR constructs to access intracellular‑derived antigens.

End‑to‑end solid‑tumor CAR‑T development—from antigen/scFv discovery and CAR optimization to cell engineering, in‑vitro/in‑vivo efficacy, and IND support. Incorporates dual/logic‑gated and armored CARs, plus trafficking and persistence enhancements to overcome the tumor microenvironment and improve safety and translation.

End‑to‑end allogeneic cell therapy development—covering donor strategy, multiplex genome editing for safety/immune evasion, scalable manufacturing and comparability, and IND/CMC support—across CAR‑T/CAR‑NK and other donor‑derived modalities to enable off‑the‑shelf access.

Configurable TIL therapy development spanning tumor processing, TIL isolation/rapid expansion, functional and phenotypic qualification, and release criteria—paired with manufacturing‑aligned process development and IND documentation to de‑risk scale‑up for solid‑tumor programs.

Active, stabilized G-Protein Coupled Receptors (GPCRs), prepared in native-like conformations, for high-throughput screening, ligand binding studies, and structure-based drug discovery.

The CD73 activity assay for HTS and hit-to-lead. Measure specific activity of CD73 in a simple mix-and-read format. The kit is designed for compound library screening and follow-up inhibitor discovery.

Blood Culture Yeast Verification Kit (RUO), Blood Culture GP Verification Kit (RUO) and Blood Culture GN Verification Kit (RUO) are designed to verify the performance of molecular testing processes that detect the presence of nucleic acids from various yeasts or bacteria. Supplied in single-use vials, these kits can also be used to train and evaluate operator proficiency.

MDx-Chex for Blood Culture Yeast (RUO), MDx-Chex for Blood Culture GP (RUO) and MDx-Chex for Blood Culture GN (RUO) are full-process molecular quality controls designed for comprehensive molecular assay workflow validation.

Achieve ultra-high RNA yields with MEGAscript™ kits—ideal for in vitro or in vivo translation studies needing unlabeled or low specific activity RNA.

UltraScript® cDNA Synthesis Kit Separate Oligos contains all the components for efficient and sensitive cDNA synthesis over a broad range of RNA template concentrations. Anchored oligo(dT) and random hexamers are provided separately for user optimisation depending on the type of analysis needed.

UltraScript 2.0 cDNA Synthesis Kit Separate Oligos containins all the components required for fast, reliable and unbiased cDNA synthesis of the most challenging RNA sample types. Anchored oligo(dT) and random hexamers are provided separately for user optimisation depending on the type of analysis needed.

UltraScript® 2.0 cDNA Synthesis Kit is a 2-tube kit containing all the components required for fast, reliable and unbiased cDNA synthesis of the most challenging RNA sample types.

UltraScript® 2.0 Reverse Transcriptase is a highly thermostable reverse transcriptase designed for cDNA synthesis of the most challenging RNA sample types. This modified MMLV reverse transcriptase can be used with reaction temperatures of over 55 °C, giving improved specificity, higher cDNA yields and more full length cDNA product.

UltraScript® cDNA Synthesis Kit is an easy-to-use 2-tube system specifically developed to generate cDNA for use in real-time PCR. The kit provides unbiased, efficient and sensitive cDNA synthesis over a broad range of RNA template concentrations.