Thermo Scientific™ Dionex™ Integrion™ HPIC™ System

Perchlorate has been used as an oxidizer in rockets, munitions, and fireworks since the 1950s. It has been found to cause thyroid dysfunction and has been linked to tumors in humans. Perchlorate is regulated under the Safe Drinking Water Act (2011) although the Maximum Contaminant Level Goal (MCLG) and Maximum Contaminant Level (MCL) have not yet been established. Explore how Thermo Fisher Scientific identifies and quantitates trace levels of perchlorate in raw and finished drinking waters according to US EPA Method 332.0 using a compact high-pressure ion chromatography (HPIC) system coupled with a single quadrupole mass spectrometer.

Over the last 45 years, ion chromatography (IC) system and column technology innovations have improved many IC applications for greater ease of execution, accuracy, consistency, and sensitivity. Thermo Fisher Scientific outlines the enhancements in ionic determinations that have resulted from innovations in IC technology. Discover how practically any IC application can be simplified, improved, and optimized for its ease-of-use.

The production of foods and beverages for human and animal consumption is governed by a whole host of regulatory agencies across the globe and also by guidelines on Good Manufacturing Practice (GMP).

In this eBook, we consider the suite of chromatography solutions from Thermo Fisher Scientific coupled with their various MS technologies (and other add-ons) through case studies demonstrating their application in QC testing of a wide range of food and beverage products.

Understand how these analytical methods overcome problems arising in traditional approaches, such as sample matrix interference or the need for pre-processing (e.g. derivatization), thereby enabling the high-resolution separation of complex samples at greater speed followed by high-sensitivity detection.

The development of reliable, high-throughput workflows for analysis of N-linked glycans is required in the biopharmaceutical industry. In this scientific poster, Thermo Fisher Scientific reports a novel method that couples high-performance anion-exchange chromatography and pulsed amperometric detection (HPAEPAD) to a Q Exactive mass spectrometer, a workflow that promises the fast release and subsequent analysis of N-linked glycans.

The presence of very polar ionic pesticides in surface and drinking water, as well as food and beverages, has become a controversial issue in recent years. The development of genetically modified crops tolerant to glyphosate and glufosinate, for example, promoted the use of these broad spectrum herbicides. The analysis of glyphosate and other polar compounds presents a difficult analytical challenge. Their polarity does not allow the direct analysis by reversed-phase HPLC, so alternative methods need to be applied. Derivatization of glyphosate prior to analysis or application of specific chromatographic columns, such as the Thermo Scientific™ Hypercarb™ column, are the common approaches.

The analysis of polar ionic pesticides in surface and drinking water as well as food and beverages has become a controversial issue in recent years. The development of genetically modified organism (GMO) crops tolerant to glyphosate (N-(phosphonomethyl)glycine) and glufosinate ((RS)-2-amino4-(hydroxy(methyl)phosphonoyl)butanoic acid), for example, promoted the use of these broad spectrum herbicides. In addition, glyphosate is used as a crop desiccant and to suppress weeds in parks and at roadsides. Consequently, polar pesticides are found in foods as residues and in the environment as contaminants of surface waters and soils.

Learn an IC-MS/MS multi-residue method for high-throughput screening and quantitation of polar pesticide residues and their metabolites in food matrices below the current legislative requirements.

Learn about an IC-MS/MS based method for the high-throughput screening and quantitation of polar pesticide residues and their metabolites in water matrices below the current legislative requirements.

This application note demonstrates a method for determining glucose, fructose and sucrose concentrations in a 100-fold diluted alcoholic beverage sample, in this example a scotch liqueur sample. The method used is HPAE-PAD on a Thermo Scientific™ Dionex™ Integrion™ RFIC™ system equipped with a 0.4 μL internal injection loop and the Thermo Scientific™ High Concentration Carbohydrate Analysis Kit1.

This application note demonstrates a high-performance anion-exchange with pulsed amperometric detection (HPAE-PAD) method to accurately determine sugar concentrations. In this proof note, the method is performed using a Thermo Scientific™ Dionex™ Integrion™ HPIC™ system, which allows fast determination of sugars in functional drinks, such as sports and energy drinks, with no eluent preparation or sample derivatization.

In this presentation, Chris Pegg, Senior Scientist Chemistry at Anglian Water, discusses the benefits of ion chromatography for determining bromate, chlorate and iodide content in water.

Simon Ellison, Sales Support Manager for Chromatography and Trace Elemental products at Thermo Fisher Scientific, introduces the capabilities of the Hemel Hempstead laboratory facility. This centre of excellence enables scientists to solve their problem to improve results.

Hear from Wai Chi Man, Technical Specialist, Ion Chromatography, Thermo Fisher Scientific, explain the range of environmental applications that can benefit from ion chromatography technology.

Thermo Scientific anionic pesticides explorer delivers high-throughput detection, identification and quantification of anionic polar pesticides in compliance with the latest EU regulations

Wai Chi Man, Technical Specialist at Thermo Fisher Scientific, explains how ion chromatography can improve water contaminant analyses

Meeting the demands of the food and beverage industry with advances in technology

SelectScience® spoke to Dr Guangchao Li, Technical Director of the Environmental Measurements Facility at Stanford University, about the technology enabling his research

Thermo Scientific Dionex Integrion High-Pressure Ion Chromatography (HPIC) system breaks new ground in productivity and efficiency for environmental, food safety, pharmaceutical and industrial/petrochemical laboratories