Next Generation Sequencing Products & Reviews

Agilent HaloPlex panels are predefined designs which focus on targeted gene sets for specific applications. Agilent offers two catalog HaloPlex panels, the Cancer Research Panel and the Cardiomyopathy panel.The HaloPlex Cardiomyopathy (catalog) is a next generation sequencing target enrichment panel designed specifically for inherited forms of cardiomyopathy. Following a careful review of cardiomyopathy publications as well as…

The SureSelect Focused Exome is a highly targeted design that enables analysis of only disease-associated targets, enabling superior coverage of disease-associated regions even on benchtop sequencers. This design provides 20 or more reads for 95% of targets at 1.5Gb (100x) of sequencing and 98% of targets with 3Gb (200x) of sequencing.

The Magnis system provides a complete workflow for NGS library preparation that is fully automated and delivers reproducible results. Built on proven Agilent SureSelect XT HS2 chemistry, start from total RNA with integrated cDNA conversion or unfragmented DNA with onboard enzymatic fragmentation for increased workflow efficiency.

Unlock the full potential of molecular diagnostics on a single platform

SureSelect Cancer CGP assay offers comprehensive genomic profiling for solid tumors. This pan-cancer NGS panel enables detection of somatic variants, including single nucleotide variants (SNVs), copy number variants (CNVs), insertions/deletions (indels), translocations (TLs), gene fusions, and the immuno-oncology biomarkers TMB (tumor mutational burden) and MSI (microsatellite instability).

Designed for smaller studies, the SureSelect DNA Capture Arrays complement Agilent's in-solution SureSelect Target Enrichment System, which is designed for medium to large-scale NGS studies of tens through thousands of samples, including automated high-throughput workflows.

Agilent’s market leading SureSelect platform provides a complete portfolio of catalog and custom products, providing the flexibility you need from discovery to follow-up studies. Agilent’s custom solutions offer the only available method for target enrichment of RNA, allowing you to target your regions of interest using our free web portal SureDesign. Custom solutions are available for DNA and RNA target enrichment. • The only…

SimpliFY Your Clean Ups. Microlab PuriFY offers a compact, standalone solution for automated nucleic acid bead-based clean-up for NGS library preparation and PCR, enabling scientists to spend less time of tedious, repetitive tasks and more time concentrating on their vital research.

Space-Saving, On-Deck Fluorescence Measurements. The Fluoreye mobile fluorescence reader is operated by a 1000 µL pipetting channel, moving to and measuring samples in 96-well flat-bottom plates.

The power of Fontus™ automation. Making waves in NGS library prep.

Clean up and size selection of DNA and RNA for NGS workflows using magnetic beads

Removal of unincorporated terminators from sequencing reactions using magnetic beads

Fluorescent Annexin V conjugates that are optimized for bright and low background staining of extracellular vesicles for flow cytometry.

BioIVT provides isolated exosomes from a variety of human, animal, and plant sources, as well as custom characterization and in vitro assays investigating function and potential therapeutic benefit.

The Protein A kit is a ready-to-use assay for antibody quantification with the Amperia™ system. Using Fc capture and an inverse-occupancy format, it delivers reproducible titres directly from crude or clarified samples. Each kit supports up to 320 tests, simplifying workflows from clone screening to process development.

The AAVX and AAV9 Total Capsid Quantification Kits extend the Amperia™ Protein Quantification System for streamlined measurement of adeno-associated virus (AAV) vectors. Incorporating CaptureSelect™ affinity reagents from Thermo Fisher Scientific, the kits provide robust, reproducible assays for both broad serotype coverage and AAV9-specific quantification.

Automated Purification of High-Quality Total RNA with an Enhanced miRNA Enrichment

The Twist FlexPrep™ UHT Library Preparation Kit streamlines ultra-high throughput sequencing by integrating Normalization by Ligation™ technology, enabling efficient sample processing for population studies and agrigenomics.

Twist’s Fast Hybridization and Wash Kit is a revolutionary new system with the flexibility to both save you time and improve the performance of your targeted sequencing efforts. It accommodates your samples, your schedule, and your performance needs: accelerate hybridization to as little as 15 minutes, or adjust the hybridization time to improve coverage for all targeted sequencing applications, including whole exome, custom…

Twist Universal Blockers enhance the specificity of next-generation sequencing (NGS) target enrichment by preventing non-specific hybridization between adapter sequences, thereby improving on-target capture and reducing sequencing costs.

The Twist Universal Adapter System enhances the performance of 'T-A' overhang ligation library preparation workflows in next-generation sequencing (NGS) by reducing adapter dimer formation and increasing library yield.

Twist also offers Research-Use Only (RUO) target enrichment NGS panels for viral detection and characterization of samples. These panels can be used for environmental monitoring and surveillance testing, while also providing insight into full sequence information for monitoring of viral evolution and strain origin.

The superior performance of Twist Human Core Exome provides the optimal solution for sequencing of protein coding genes. The Twist Human Core Exome however focuses only on the most accurate curated subset—CCDS database. Twist now offers the Twist Human RefSeq Panel, which is designed to expand the content of the Twist Human Core Exome. When combining the two panels, greater than 99% of protein coding genes are covered.

Twist Library Preparation Kit (Mechanical Fragmentation) is designed for use with gDNA that has already been sheared mechanically. It combines the enzymes and reagents for end repair, dA-tailing, and adapter ligation into a single reaction: Accommodates a wide range of DNA input types, enables high-quality sequencing of low-quality samples and minimizes start / stop site artifacts

Twist Library Preparation EF Kit (Enzymatic Fragmentation) incorporates the reagents and enzymes needed for DNA fragmentation with those for end repair, dA-tailing, and adapter ligation into a single reaction:  Ideal for automated, high-throughput library preparation, produces tunable, reproducible fragment sizes and minimizes sequence bias, maximizes coverage depth.