Products & Reviews

Next-generation sequencing (NGS) technologies have dramatically reduced sequencing costs and led to novel approaches in many fields of biology.

Effective genomic surveillance of SARS-CoV-2 variants begins with the right tools 

Accurate and sensitive quantification of DNA, RNA, and protein with flexible throughput

SPRIselect is a SPRI-based chemistry that speeds and simplifies nucleic acid size selection for fragment library preparation for Next Generation sequencing. In this process, size selection is required to produce a uniform distribution of fragments around an average size. Using SPRIselect, the size distribution can be adjusted to suit the application and platform used. The process can be scaled for low to high throughput workfl…

Superior Size Selection and Recovery for NGS and PCR

Twist Custom Panels can be designed and built to cover a wide range of panel sizes, target regions, and multiplexing requirements — all with exceptional and consistent performance. Whether you design your own panel from scratch or add targets to enhance the content of existing panels, you can use your Twist Custom Panel with Twist’s modular library preparation kits or seamlessly integrate them into an existing workflow.

Twist Bioscience, the leader in synthetic DNA with unparalleled precision at scale, is redefining targeted sequencing performance with the Twist Human Core Exome Kit. This kit includes library preparation and enrichment components, allowing the flexibility to lower sequencing costs, increase sample throughput, and achieve a higher depth of coverage across target regions with uncompromising quality.

Exome sequencing has become a widely used practice in clinics and diagnostics. The superior performance of the Twist Human Core Exome provides the optimal solution for sequencing of protein coding genes, while focusing on the most accurate curated subset— CCDS database.

Positive controls provide quality control measures for the verification and validation for point-of-care diagnostic tests including both next-generation sequencing (NGS) and reverse transcriptase-polymerase chain reaction (RT-PCR) assays. Twist offers fully synthetic SARS-CoV-2 RNA controls, available for dozens of distinct reference sequences.

Twist Library Preparation Enzymatic Fragmentation (EF) Kit 2.0 is built to help you achieve a more efficient sequencing pipeline and obtain more accurate Next-Generation Sequencing (NGS) results. This updated kit has new fragmentation and ligation modules, and includes the Equinox Library Prep Amp Mix. This hot-start enzyme formulation has a lower error rate* and high efficiency at low input volumes—making it ideal for samples…