UHPLC and HPLC Products & Reviews

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High performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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SkillPak 50 and 200 pre-packed columns

Tosoh Bioscience

SkillPak 50 (2.5 cm ID x 10 cm L, CV 50 mL) and 200 (5 cm ID x 10 cm L, CV 200 mL) pre-packed columns offer a reproducible and efficient solution for developing purification methods for biomolecules. They are the best solution to scale up methods developed on SkillPak 1 and 5 mL pre-packed columns.

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Inertsil Hybrid-C18 LC Column

GL Sciences, Inc.

Inertsil Hybrid-C18 is a high-pH resistant HPLC column that enables stable and reproducible separations across a wide pH range (1–12). Built with hybrid silica technology, it ensures excellent peak shapes even for basic analytes and provides superior lifetime compared to conventional C18 columns. Available in 1.7 µm, 3.5 µm, and 5 µm, it is ideal for LC-MS and method development.

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ProteoSil BioLC Column

GL Sciences, Inc.

GL Sciences' Bio LC Columns "ProteoSil" are tailored HPLC solutions designed specifically for proteomics and the analysis of bio molecules such as proteins, peptides, and nucleic acids. The packing materials used in these columns are crafted from high-purity silica, offering pore sizes of 100Å, 200Å, and 300Å. They are available in multiple configurations, including reversed phase, HILIC, and size exclusion columns.

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Empower Software

Waters | Wyatt Technology

Empower™ Software Solutions supports the collection, processing, and reporting of data from DAWN™ multi-angle light scattering (MALS) and Optilab™ differential refractive index (RI) instruments.

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Avantor® ACE® Excel Columns

Mac-Mod

Designed to take advantage of low dispersion, ultra-high pressure UHPLC instruments, Avantor® ACE® Excel UHPLC columns give chromatographers more choices to achieve better results

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