UHPLC and HPLC Products & Reviews

"Extend-C18 columns incorporate a unique patented bidentate silane, combined with a double-endcapping process that protects the silica from dissolution at high pH - up to pH 11.5. Columns are best applied for separations of compounds that are either (1) basic and have little or no retention at low or intermediate pHs, (2) more stable or more soluble at high pH, or (3) basic and show poor peak shape at low or intermediate pH.…

Specialized Columns for Mixed Polar and Nonpolar Compounds.

The Ultra line represents Restek’s broadest selection of stationary phases on a single silica support.Made of high-purity, type-B silica that minimizes activity and creates high-density bonding, the Ultra Amino Columns (USP L8) are designed for selective and reliable HPLC applications. Particle size: 3 μm or 5 μm, spherical Pore size: 100 Å Carbon load: 2% End-cap: no pH range: 2.5 to 8 Temperature limit: 80 °C USP phase code…

The Ultra line represents Restek’s broadest selection of stationary phases on a single silica support. Made of high-purity, type-B silica that minimizes activity and creates high-density bonding, the Ultra Cyano Columns (USP L10) are designed for selective and reliable HPLC applications.Particle size: 3 μm or 5 μm, spherical Pore size: 100 Å Carbon load: 8% End-cap: yes pH range: 2.5 to 8 Temperature limit: 80 °C USP phase co…

The Ultra line represents Restek’s broadest selection of stationary phases on a single silica support. Made of high-purity, type-B silica that minimizes activity and creates high-density bonding, Ultra Silica Columns (USP L3) are designed for selective and reliable HPLC applications. Particle size: 3 μm or 5 μm, spherical Pore size: 100 Å End-cap: no pH range: 2.5 to 8 Temperature limit: 80 °C USP phase code: L3 Phase catego…

Viva columns are based on a wide pore material we designed for optimal large-molecule separations.In developing Viva silica, we found that although many commercial wide-pore silicas meet the standard 300 Å mean pore size, most have very broad distributions about this mean, with a significant portion of their pore volume falling below 150 Å.This means a large portion of the surface area is unavailable to larger molecules. Viva…

Use our bulk packing materials to pack your own columns. Our extensive QC program ensures the high quality and reproducibility of these silicas. You can be confident that you are getting consistent, high-quality product when you source your silica from Restek. Use these materials for easy scale-up to preparative chromatography or for packing your own columns. Ultra Bulk Packing Materials Features: Prepare your own columns…

Get more of what you want, and less of what you don't, with Roc™ LC columns from Restek.

Force LC columns are available with Restek's most popular and highly selective Biphenyl and FluoroPhenyl phases, as well as a general-purpose C18.

Restek's Raptor FluoroPhenyl column offers the ability to run in reversed-phase or HILIC mode for a variety of compounds. It is ideal for increasing sensitivity and sensitivity in LC-MS analyses. 

The Allure Acrylamide LC column provides targeted acrylamide retention as well as improved isolation from matrix interferences.

Designed with you in mind.

Rapid at-line analytical chromatography solution for all stages of mRNA production, purification, and quality assessment.

Innovative solution that enables investigation of multiple critical attributes for LNP drug products, without extensive sample preparation or dye requirements.

A tool for chromatographic purification of LNPs as an alternative to filtration methods.

BioRenewable, gradient grade for liquid chromatography, LiChrosolv®, reag. Ph. Eur.

BioRenewable, gradient grade for liquid chromatography LiChrosolv® Reag. Ph Eur

This new strong anion exchange resin offers an optimised macro-porous structure that ensures an efficient purification of large biomolecules, such as adeno-associated viruses (AAVs) and plasmid DNA (pDNA). With its high binding capacity for such molecules and high separation efficiency even at elevated flow rates, MacroSep IEX Q is a perfect addition to DSP platforms.

Bioinert coated YMC Accura BioPro IEX columns provide excellent peak shapes for sensitive compounds, ensuring high recovery from the very first injection.

YMC-Actus prepacked (semi-)preparative HPLC columns show high stability and long lifetimes even under high flow rates and steep gradient conditions without any void volume formation.

BioPro IEX, YMC's strong ion exchange material are based on a hydrophilic polymer which provides low non-specific adsorption and high recoveries. Porous and non-porous polymer beads are available for high loadability and throughput.  

YMC provides silica-based SEC phases with a dihydroxypropyl modification in 4 different pore sizes.

YMC-SEC MAB is a silica-based size exclusion chromatography column utilizing a dihydroxypropyl stationary phase bonded to a silica gel base, specifically designed for antibody separations.

BioPro HIC columns based on non-porous hydrophilic polymer beads and functionalised with butyl chains are optimised for the analysis of antibodies, antibody-drug conjugates (ADCs) and other proteins.

With YMC-Triart Prep, pH stable preparative HPLC stationary phases are available for industrial-scale applications. This hybrid silica-based material can be used in a pH range of 2.0 - 10.0 and allows more efficient cleaning procedures. The innovative YMC-Triart Prep combines mechanical strength and pH stability.