Robust and pH stable process chromatography material: YMC-Triart Prep
With YMC-Triart Prep, pH stable preparative HPLC stationary phases are available for industrial-scale applications. This hybrid silica-based material can be used in a pH range of 2.0 - 10.0 and allows more efficient cleaning procedures. The innovative YMC-Triart Prep combines mechanical strength and pH stability.
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To overcome the limitations of traditional silica-based stationary phases regarding the chemical stability, hybrid silica-based phases have been developed. Hybrid silica contains organic groups within the silicon dioxide network, making it more resistant to a wider pH range.
The innovative preparative stationary phase YMC-Triart Prep combines mechanical strength and pH stability. It is stable up to pH 10 which allows more flexibility for process development. Moreover, efficient cleaning-in-place (CIP) procedures can be applied!
From real-life process development examples, YMC-Triart Prep has been shown to outperform traditional silica-based materials in terms of stability up to 4-fold. Longer column lifetimes lead to greater amounts of product being produced per kilogram of stationary phase. The results mean improved production procedures and reduced overall costs.
YMC-Triart Prep Features:
- Mechanical stability
- Extended pH range
- CIP with NaOH solutions applicable
- Up to 4-fold longer lifetimes
- Compatible with SMB and SFC mode
- Available as packing material in multi-ton scale and in preparative columns
YMC-Triart Prep Characteristics:
- Modifications: C18, C8, Phenyl
- Particle sizes: 7, 10, 15, 20 µm
- pH range: 2 - 10
- Separation modes: RP, SFC, SMB
