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Robust and pH stable process chromatography material: YMC-Triart Prep

YMC EuropeAvailable: Worldwide

With YMC-Triart Prep, pH stable preparative HPLC stationary phases are available for industrial-scale applications. This hybrid silica-based material can be used in a pH range of 2.0 - 10.0 and allows more efficient cleaning procedures. The innovative YMC-Triart Prep combines mechanical strength and pH stability.

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To overcome the limitations of traditional silica-based stationary phases regarding the chemical stability, hybrid silica-based phases have been developed. Hybrid silica contains organic groups within the silicon dioxide network, making it more resistant to a wider pH range.

The innovative preparative stationary phase YMC-Triart Prep combines mechanical strength and pH stability. It is stable up to pH 10 which allows more flexibility for process development. Moreover, efficient cleaning-in-place (CIP) procedures can be applied!

From real-life process development examples, YMC-Triart Prep has been shown to outperform traditional silica-based materials in terms of stability up to 4-fold. Longer column lifetimes lead to greater amounts of product being produced per kilogram of stationary phase. The results mean improved production procedures and reduced overall costs.

YMC-Triart Prep Features:

  • Mechanical stability
  • Extended pH range
  • CIP with NaOH solutions applicable
  • Up to 4-fold longer lifetimes
  • Compatible with SMB and SFC mode
  • Available as packing material in multi-ton scale and in preparative columns

YMC-Triart Prep Characteristics:

  • Modifications: C18, C8, Phenyl
  • Particle sizes: 7, 10, 15, 20 µm
  • pH range: 2 - 10
  • Separation modes: RP, SFC, SMB

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