Corning Matrigel Matrix for Organoids by Corning Life Sciences
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Status:
Advanced Reviewer
Member since: 2011
Organization: CIBERONC-IIB
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- Ease of use
- After sales service
- Value for money
High quality product and fantastic customer service.
Application Area: Patient-derived normal and tumoral colon organoids
"Fantastic product, following the manufacturer's instructions there is no problem in its handling. Very good customer service where they advise how to improve the management of your 3D cultures."
Review date: 13 Feb 2020 | Corning Matrigel Matrix for Organoids
Status:
Reviewer Member since: 2020
Organization: University of Toronto
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- Ease of use
- After sales service
- Value for money
Good for 3D collagen gels.
Application Area:3D tissue culture (collagen gel)
"Good for 3D collagen gels, improves, cell proliferation and differentiation compared to collagen only constructs."
Review date: 28 Jan 2020 | Corning Matrigel Matrix for Organoids
An optimized extracellular matrix that provides a convenient, ready-to-use solution, verified to support organoid growth and differentiation
Corning’s new Matrigel matrix for organoid culture is formulated to support organoid growth and differentiation. It is a convenient, ready-to-use solution that provides the consistency and reliability needed for successful organoid culture by employing the following steps:
Each lot is measured for its elastic modulus, which is indicative of matrix stiffness and is qualified to form stable "3D dome" structures commonly used in organoid culture. Verified to support growth and differentiation of mouse and human organoid cultures including:
- Long-term expansion of mouse small intestinal organoids for more than 7 passages with typical organoid budding morphology and marker expression
- Growth and differentiation of polarized 3D organoids from primary human airway epithelial cells expressing typical markers
Corning’s new Matrigel matrix reduces the need for time-consuming screening, while providing the reproducibility and consistency essential for organoid research.
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