CellTrypase
Animal-origin-free recombinant trypsin alternative for cell dissociation in cell therapy, stem cell and biomanufacturing workflows
Place your order directly with the manufacturer.
CellTrypase is a high-purity, animal-origin-free recombinant trypsin-like enzyme for reliable cell dissociation in research and biomanufacturing workflows. Available in R&D and GMP grade, CellTrypase supports cell culture, stem cell, cell therapy, viral vector and bioprocessing applications where consistent performance, supply reliability and regulatory readiness are important. CellTrypase can be evaluated as a high-quality alternative or second source to established trypsin-based cell dissociation solutions such as TrypLE™ (Trademark of Thermo Fisher Scientific Inc.).
Benefits of CellTrypase:
- Gentle & reliable: Consistent, efficient cell dissociation while preserving cell viability and function
- Highest purity for consistent cell culture results
- Full, in-house manufacturing under certified GMP/GDP quality standard
- Better value: Equivalent performance at optimized quality and lower cost.
- Demonstrated performance across key biopharma production cell lines, including CHO-K1, HEK293, MDCK, Vero and iPSC-based workflows.
- Available in R&D + GMP grade with identical specifications
For customers considering the replacement of a trypsin-like enzyme in your approved manufacturing process - Kerry's Change Guidance Documents help you navigate raw and ancillary material changes with confidence, using a regulatory-aligned framework.
Brochures
Frequently asked questions about CellTrypase
This resource answers frequently asked questions regarding CellTrypase. It covers general aspects, how to use and apply CellTrypase, the enzyme characteristics and differences especially in context to comparison with competitor products, like TrypLE™, and some questions regarding the supply chain and manufacturing.
Resource details:
Resource type: Product Brochure
Page count: 4
Read time: 6 mins
Guidance on qualification of CellTrypase in biopharmaceutical manufacturing processes
As CellTrypase may be considered a critical raw material in some processes, thorough qualification is essential. This guidance highlights key regulatory considerations, qualification best practices for biomanufacturing processes, and the support Kerry provides for a smooth, compliant transition.
Resource details:
Resource type: Product brochure
Page count: 6
Read time: 10 mins
CellTrypase: Gentle and reliable cell dissociation in biomanufacturing
This Application Note summarizes the key characteristics and performance metrics of CellTrypase for biopharmaceutical applications. Included are comparative analyses across standard production cell lines (CHO-K1, HEK293, MDCK, and Vero), together with performance assessments in advanced cellular models, including human induced pluripotent stem cells (iPSCs) cultured in both 2D and 3D formats.
Resource details:
Resource type: Application note
Page count: 9
Read time: 12 min
Advancing cell dissociation in bioprocessing: a novel, high purity trypsin-like enzyme for GMP workflows
This poster introduces a novel GMP-grade recombinant enzyme of fungal origin, designed to enable gentle and consistent cell dissociation across a wide range of applications. CellTrypase was evaluated across a range of standard and advanced cell types (including iPSCs) and compared to the current industry standard.
Resource details:
Resource type: Scientific Poster
Page count: 1
Read time: 2 mins
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