Antibody Humanization Service
Sino BiologicalSino Biological offers top-notch monoclonal antibody humanization services utilizing complementarity-determining region (CDR) grafting technology and computer-aided molecular modeling.
Life sciences encompass a diverse range of scientific disciplines focused on the study of living organisms and their interactions with the environment. From basic life sciences (such as cell biology, genetics, immunology, and microbiology) to applied life sciences (such as disease research, multi-omics, and biotechnology), this broad field explores the fundamental processes of life and drives advancements in disease research, patient care, and our overall understanding of living organisms. Discover the endless possibilities of life sciences and their impact on shaping a healthier and more sustainable world.
Sino Biological offers top-notch monoclonal antibody humanization services utilizing complementarity-determining region (CDR) grafting technology and computer-aided molecular modeling.
Protein A chromatography resin with enhanced alkaline stability and binding capacity for improved process economy in antibody purification.
Wire myography is an in vitro technique that allows us to examine functional responses and vascular reactivity of isolated small resistance arteries. Vessels from various species, including transgenic models, and vascular beds can be examined in a variety of pathological disease states. Vessels are dissected, cleaned, and then mounted onto a channel myograph under isometric techniques. Each vessel is then normalized to determi…
Gyrolab® Generic Rodent ADA Kit Reagents enable detection of anti-drug antibodies of human IgG or Fab in rodent matrices including mouse and rat.
Scintica’s micro PVC phantoms are available in 3 sizes (27 mm OD, 34 mm OD, and 49 mm OD). These phantoms consist of one custom manufactured component and three separate pieces of commercial hardware for assembly. They have three separate voids, one with a series of spheres for a contrast recovery curve, one with a separately fillable warm background, and a final separate reference volume that can be optionally filled.
The Gyrolab® Mouse IL-4 Kit enables rapid quantification of murine IL-4 in serum samples
The Quanterix Simoa® ALZpath p-Tau 217 Assay provides an ultrasensitive, reliable solution for detecting phosphorylated Tau 217 (p-Tau 217) in blood. This critical biomarker is essential for Alzheimer’s research, offering insights into disease progression and helping differentiate Alzheimer’s from other forms of dementia.
Optimized for high-yield synthesis of pseudouridine-containing, in vitro transcribed RNA (Ψ-RNA). Produce up to 60 µg of Ψ-RNA from 1 µg of template in 2 hours. Easily scale up to produce milligram amounts of Ψ-RNA. Induce lower innate immune responses in mammalian cells by using Ψ-mRNA.
"Derenzo" phantoms are used to characterize an imaging system's resolution by measuring the FWHM of hole patterns with varying diameters and spacing. Holes within a size group are spaced at exactly 2D (twice the diameter) apart. Our Derenzo phantoms feature six different hole sizes arranged in triangles around the center of phantom.
PCRBIO Taq Mix is an affordable, versatile and robust 2x mix for all your everyday PCR applications including genotyping, screening and library construction. An enhanced 12-step polymerase purification strategy together with an optimised buffer system enable PCRBIO Taq Mix to amplify with the highest speed, yield and specificity.
The iLite® C5a Assay Ready Cells can be used for the quantification of C5a activity, and for determination of inhibitory activity against either C5a itself or against the C5a receptor in test samples, including human serum.
NanoDrop UltraC combines pedestal and cuvette absorbance measurements, expanding its versatility for various sample types. It offers high sensitivity and reliability for both concentrated and dilute samples, making it ideal for comprehensive analytical needs in research and production environments.
The AAV-TAb custom ELISA allows for the determination and quantification of total antibody binding to AAV vectors of different serotypes, including any potential custom capsid. This is achieved using your unique AAV preparation, eliminating the need for a surrogate AAV. Embrace the simplicity and flexibility of our two-step ELISA TAb.
Cost Effective Widefield Fluorescence Microscopy
SignalChem (Part of Sino Biological) offers tailored contract research services ranging from enzyme development and compound profiling to assay development.
For post-transcriptional poly(A) tail addition to RNAs. Tail mRNAs in vitro to lengths equivalent to or greater than those found in nature.
Small in Size, Super in Resolution
Co-transcriptionally cap 5-methyl-cytidine- pseudouridine-containing, in vitro transcribed RNA with Anti-Reverse cap analog (ARCA). Produce up to 40 µg of capped 5mCΨ-RNA from 1 µg of template in 3 hours. Optimized for maximum transcript capping and yield. Induce lower innate immune responses in mammalian cells by using 5mCΨ-mRNAs.