Products & ReviewLife Sciences

AAV Total Capsid Quantification Kits | AAVX & AAV9

AbselionSKUs: AK-AAV-002 (AAVX), AK-AAV-003 (AAV9)

The AAVX and AAV9 Total Capsid Quantification Kits extend the Amperia™ Protein Quantification System for streamlined measurement of adeno-associated virus (AAV) vectors. Incorporating CaptureSelect™ affinity reagents from Thermo Fisher Scientific, the kits provide robust, reproducible assays for both broad serotype coverage and AAV9-specific quantification.

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Description

Designed for scientists working across gene therapy research and development, the AAVX and AAV9 kits simplify total capsid measurement by reducing the need for in-house assay optimisation. Each kit is supplied in a ready-to-use format with sensor strips, reagents, and pre-set assay templates for seamless integration with the Amperia™ system. The assays use a sandwich-style immunoassay with electrochemical detection, enabling accurate quantification from both purified and complex samples.

Key Features

  • Ready-to-use format tailored for the Amperia™ system
  • Incorporates CaptureSelect™ affinity reagents for specificity and consistency
  • Sandwich immunoassay with electrochemical detection — no optics or fluidics required
  • Supports both purified preparations and in-process samples
  • Pre-set templates for straightforward assay setup

Applications

  • Total capsid quantification in AAV research and development
  • Process development and optimization in gene therapy workflows
  • Monitoring titres across upstream and downstream steps
  • Comparative studies across serotypes or process conditions
Application NoteLife Sciences

Empowering AAV quantification for gene therapy research

Adeno-associated virus (AAV) vectors have become a cornerstone of gene therapy, valued for their safety, broad targeting capabilities, and adaptability across therapeutic applications.

In this application note, Abselion demonstrates the Amperia™ platform, offering a streamlined alternative – using a sandwich-format assay with high-affinity antibodies from Thermo Fisher Scientific to quantify multiple AAV serotypes with robust performance across sample types.

TechTalk: Fast, accurate, accessible quantification across diverse biologics

Friday, January 23 at 16:00 GMT | 17:00 CET | 11:00 EST | 08:00 PST

Quantifying antibodies, AAV capsids, and tagged proteins directly from crude or partially clarified samples remains a common bottleneck in many biologics workflows.

In this 20-minute TechTalk, Dr. Paolo Romele, VP of Science, Abselion will introduce the electrochemical approach used in the Amperia™ benchtop platform, which combines affinity-based capture with Redox Electrochemical Detection (RED) to provide quantitative measurements without relying on optical readouts.

Join this educational and technology-focused session to learn practical examples illustrating how these assays operate across biologics applications.

Key learning objectives:

  • Understand the principles behind affinity-based electrochemical assays using Redox Electrochemical Detection (RED) as implemented in the Amperia™ system.
  • Learn how the three assay formats are applied to antibodies, AAV capsids, and tagged proteins.
  • Review example data demonstrating assay behaviour with directly prepared samples.
  • See how electrochemical detection can complement existing analytical approaches in biologics measurement.

Who should attend?

  • Biotech and pharma scientists working with antibodies, AAV vectors, tagged proteins, protein expression, cell line development, or vector optimization.
  • Research teams in early development focused on process design, screening, assay development, and exploring quantification methods beyond traditional optical assays.

Certificate of attendance
If you attend the live TechTalk, you will automatically receive a certificate of attendance, including a learning outcomes summary, for continuing education purposes.

If you view the on-demand TechTalk, you can request a certificate of attendance by emailing editor@selectscience.net.

Product Overview

Links

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The His-Tag Protein Quantification Kit extends the Amperia™ Protein Quantification System for direct, tag-specific measurement of His-tagged recombinant proteins. Using a premix competition format with GenScript’s THE™ His Tag Monoclonal Antibody, the kit delivers accurate, reproducible results across both crude lysates and purified samples, with up to 80 tests per kit.

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Amperia™ Protein Quantification System

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The Amperia™ system combines compact hardware, assay-ready sensors, and integrated software to streamline protein quantification. Built to support scientists in discovery, development, and beyond, it delivers dependable data quickly and without unnecessary complexity — even from crude or complex samples.

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