LGC Diagnostics and Genomics - Biosearch Technologies Oligo-Synthesis Products & Reviews

Dual-labelled probes featuring the original BHQ dye technologies

Compact PCR probes for detecting difficult target sequences

Custom design your oligonucleotide according to your specifications. Our probes and primers are manufactured at unmatched quality under ISO 9001 and 13485 compliance. Whether you need RUO or GMP grade oligos, choose from a vast selection of modifications to customize your oligos for your application.

Keep up with fluctuating testing demands in an economically viable way due to minimized labor costs enabled by automated sample processing, amplification, and data analysis workflows.

The MerMade 12 Oligonucleotide synthesizer is designed to synthesize DNA, RNA and LNA oligonucleotides in a column format using standard or modified chemistries.  

RNA visualization method that allows simultaneous detection, localization, and quantification of individual mRNA molecules

Molecular Beacons are a type dual-labeled FRET probes incorporating a quencher and a fluorophore reporter molecule. They differ from traditional dual-labeled probes, due to the incorporation of a short (~5 b.p.) complementary stem sequence at the 3' and 5' ends.

Appropriate for COVID-19 detection.

The FailSafe™ PCR System provides dependable, consistent high-fidelity PCR results for every DNA template, regardless of its source or sequence. The FailSafe PCR System will faithfully amplify your template every time. The system includes the FailSafe™ PCR Enzyme Mix and a meticulously tested set of 12 FailSafe™ PCR “PreMixes” that cover a matrix of enzyme-specific PCR conditions that are optimal for amplifying different se…

Double-quenched probes that offer improved quenching over longer probe sequences

Formulated with diagnostic kit developers in mind, RapiDxFire™ qPCR 5X Master Mix glycerol free (GF) can be combined with gene-specific primers and hydrolysis probes for immediate use in high-throughput laboratory developed test (LDT) workflows or further processed for lyophilisation for use in point of care (POC) devices. Provided at a 5X concentration without passive reference dye, this flexible master mix allows more room…

A dual-labelled probe that combines a hairpin structure and a PCR primer element in a single oligo, allowing for target detection through a unimolecular mechanism. Mismatched hybrids are less stable than the reformed stem region. Therefore, Scorpions Primers only produce signal when the probe region hybridizes to a perfect-match target sequence within the primer extension product. 

Improve assay sensitivity and specificity with Locked Nucleic Acid oligonucleotides (LNA oligos). LNAs are modified RNA bases in which the ribose is “locked” with a methylene bridge, connecting the 2' oxygen atom to the 4' carbon atom, fixing it in the C3'-endo conformation.  

Licence-free MGB probes for any application

Accelerating drug discovery with better oligos

Phosphoramidite for the incorporation of an abasic spacer internally or at the 5' end of an oligonucleotide.

Phosphoramidite used to incorporate a 5' biotin functionality, separated from the oligonucleotide by a photo-cleavable linker.

Phosphoramidite used to incorporate the cyanine-3 dye moiety into an oligonucleotide.

CPG for incorporation of an (otherwise unmodified) reverse (5' to 3') dT nucleobase at the 3' end of an oligonucleotide.  

CPG used to add the non-fluorescent quencher BHQ-1 dye to the 3' end of an oligonucleotide.

CPG for incorporation of unmodified DNA base at 3' end of an oligonucleotide.

CPG for incorporation of unmodified DNA base at 3' end of an oligonucleotide.

CPG for incorporation of unmodified RNA base at 3' end of an oligonucleotide.

CPG for incorporation of unmodified RNA base at 3' end of an oligonucleotide.

CPG for incorporation of unmodified DNA base at 3' end of an oligonucleotide.