Host cell protein (HCP) ELISA detection kits
The host cell protein (HCP) ELISA detection kits allow you to detect the presence of host cell protein impurities in your therapeutic at any phase of your product development
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The kits are designed specifically for HCP detection in your gene expression system. All reagents needed to quantify host cell protein contamination for up to 24 samples are included:
- Detect and quantify HCP concentrations at any point in your purification process
- ELISA-based: quick, familiar format with high sensitivity
- HCP Kits for multiple gene expression systems, including CHO, E. coli, Pichia, and Protein A
- 96-well plate coated with capture antibody
- HCP standards
- Reporting antibody
- Streptavidin-HRP conjugate
- TMB substrate
- 5x dilution buffer, 10x PBS-T, stop solution and plate sealers also included
Host cells used as expression systems in biopharmaceutical products contain hundreds to thousands of host cell proteins (HCPs). It is crucial to sufficiently remove HCPs from your biologic early, as high concentrations can affect the safety and efficacy of the drug. The FDA regulates that HCPs should be reduced to low levels.
