Products & ReviewLife Sciences

Gibco™ CTS™ TrueCut™ Cas9 Protein

Thermo Fisher ScientificA45220PAvailable: Worldwide

GMP-manufactured Cas9 protein for clinical research

Thermo Fisher Scientific

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Description

CTS TrueCut Cas9 Protein is our highest performing CRISPR-Cas9 protein, engineered to deliver maximum editing efficiency, including >90% in primary T cells. It is provided in a high-concentration and large-scale format for process development and clinical research applications.


Application eBookLife Sciences

Key considerations in genome editing

CRISPR gene editing has emerged as one of humanity’s most powerful technologies. Less expensive and relatively easy to design and use compared with older technologies such as zinc finger nucleases, CRISPR-Cas9 approaches are transforming biomedical science. Used initially as a tool to study gene function, the next generation of CRISPR-Cas9 tools are now allowing researchers to target almost any gene for modification in a highly specific and reliable way.

In this eBook, we take a look at the innovative suite of CRISPR-based editing tools from Thermo Fisher Scientific, how those tools can support both basic and applied research applications, and how these tools can be used to improve fidelity and efficiency along every stage of a gene editing workflow – from guide RNA (gRNA) design to cell transfection and characterization of successful edits.

Download for expert advice including how to:

  • Design your genome editing experiments with ease
  • Achieve high editing efficiency
  • Leverage CRISPR for target identification
  • Seamlessly translate your research from bench to clinic


InfographicLife Sciences

Cas9 plasmids vs proteins for CRISPR gene editing experiments

CRISPR-Cas9 systems provide a platform for direct and high-efficiency modification of genomic DNA. However, the delivery of Cas9 and synthesis of guide RNA (gRNA) remain limiting factors in the gene editing workflow.

Cas9 proteins are gaining popularity due to their promising predictability, efficiency, and robustness in delivery and editing, along with overall ease of use and time savings.

In this infographic, we outline how your CRISPR gene editing experiments can benefit from Cas9 proteins, including:

A comparison of the Cas9 plasmid vs protein workflows

The 5 key benefits of using Cas9 proteins>

A suite of next-generation Cas9 protein products >

For further information, find out how to design your CRISPR gene editing experiments in as little as five minutes with this expert article.

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