TRS100 by Agilent Technologies

Quantitative Pharmaceutical Analysis


TRS100 by Agilent Technologies product image
TRS100
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The TRS100 enables fast, easy to use whole tablet or capsule assay & polymorph analysis for pharmaceutical QC testing. Easier to implement than other spectroscopic methods, Agilent's transmission Raman spectroscopy (TRS) technology allows simple method-development and deployment in QC applications. A TRS100 system can reduce content uniformity (CU), assay, and ID tests to minutes per batch, saving significant cost and speeding up your QC workflow.

TRS100 system trays can hold up to 300 coated tablets or intact capsules, or tens of glass vials or powder samples. Sample preparation and consumables are not needed, meaning skilled analytical resource is not required. CU testing methods using transmission Raman have been approved by regulators using ICH and regulatory-authority acceptable protocols. 

Solid state Analysis: The TRS100 can be used for quantitative measurement of polymorph content in intact tablets, with LOQ of 0.1-1% w/w – significantly better than XRPD. TRS can be used for residual crystallinity in amorphous API/tablet analysis.

Features:

  • Assay hundreds of tablets or capsules in minutes
  • Works with intact capsules and coated tablets of most thicknesses
  • No sample preparation, wet chemistry or skilled testing resources needed
  • Quantifies APIs and excipients in a single measurement
  • Limit-of-Quantification as low as 0.1% w/w
  • Quantifies polymorphs in intact tablets
  • Lean calibration models - easy to build and maintain
  • Methods approved by regulators
  • A range of sample trays and accessories for tablets, capsules, liquids and powders are available