ResourceSpectroscopy

Agilent Beam Enhancer Technology for High-Speed Transmission Raman Spectroscopy

26 Feb 2019

Transmission Raman spectroscopy (TRS) is a powerful pharmaceutical analytical technique for whole-sample nondestructive capsule and tablet analysis. This Application Note describes a measurement speed increase of >10x, without increasing laser power, using an Agilent beam enhancer. With an enhancer, the active pharmaceutical ingredient % w/w in tablets was determined in as little as 10 ms.

TRS100 Quantitative Pharmaceutical Analysis System

Agilent Technologies

The TRS100 enables fast, easy-to-use whole tablet or capsule content uniformity and polymorph screening for pharmaceutical finished-product testing and formulation development. Easier to implement than other spectroscopic methods, Agilent's transmission Raman spectroscopy (TRS) technology allows simple method development and deployment for quantitative analysis in quality control applications.

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Agilent Beam Enhancer Technology for High-Speed Transmission Raman Spectroscopy