Multi-Attribute Method for OpenLab CDS
The Agilent Multi-Attribute Method (MAM) for OpenLab CDS is designed to give you just what you need to move MAM workflows from R&D to QC.
Multi-Attribute Method for OpenLab CDS
MAM solution includes software, instruments, columns, and standard
Ease of use: System performance check
System performance check - targets view
LC/MS hardware designed for performance
MAM that moves you forward
Receive your quote directly from the manufacturer.
High-resolution mass spectrometry (HRMS) and MAM have transformed biopharma drug discovery, yet QC adoption has lagged due to perceived complexity, high cost, and the need for specialized expertise. However, MAM implementation is crucial to ensure product safety, quality, and regulatory confidence.
A QC-ready, USP <1060>-aligned MAM solution now makes that possible. With modern, intuitive software and streamlined LC/MS detection on the Agilent Infinity III bio LC system with Agilent 6230C LC/TOF, QC teams can implement a MAM solution for peptide mapping without the need for expert-level MS knowledge.
Built-in capabilities, such as a ready-to-use system performance check for enhanced stability and Agilent VacShield for less downtime, ensure that methods run reliably day after day. This is MAM designed for QC: simple to deploy, easy to use, and fully aligned with regulatory expectations, so your lab can move smoothly from R&D innovation to routine QC use with confidence.
Features
- Transfer methods smoothly from R&D to QC or external labs with less complexity and lower cost using the complete, robust, and reliable Agilent MAM solution
- Save time and minimize errors with a guided step-by-step user interface
- Ensure consistent execution of methods across labs with the system performance check
- Minimize false positives and enhance fold-change detection with the novel new peak detection algorithm
- Eliminate manual data reports and get faster insights with built-in data trending and analytics
- Reduce bottlenecks by supporting multiple users with remote data analysis
- Use the Agilent Infinity III bio LC and 6230C LC/TOF as a practical alternative to highest-resolution MS/MS systems, delivering proven robustness and reducing complexity—without compromising performance
- Partner with us and rely on strong support from Agilent with in-depth mass spectrometry expertise
- Multi-Attribute Method for OpenLab CDS is an add-on software—Agilent OpenLab CDS is required
Brochures
Speed, confidence, and clarity with the Agilent MAM solution
Agilent's MAM Solutions Guide presents an integrated Multi-Attribute Method (MAM) workflow designed to support the transition of MAM from biopharmaceutical R&D into regulated quality control environments. The solution combines dedicated software, LC and LC/MS instrumentation, peptide mapping columns, standards, consumables, and compliance-ready data management tools to enable critical quality attribute (CQA) monitoring and new peak detection (NPD) workflows.
Designed around USP <1060> guidance, the platform aims to simplify method transfer, reduce training requirements, improve data integrity, streamline system suitability testing, and support routine QC implementation of peptide mapping and mass spectrometry-based product characterization. The guide highlights Agilent's focus on usability, compliance, robustness, and lower operational complexity for biopharmaceutical manufacturing and batch release applications.
Resource details:
Resource type: Product brochure
Page count: 8
Read time: 14 mins
Implement multi-attribute methods with confidence – A solution designed for biopharma QC labs
Thursday, July 23 at 16:00 BST | 17:00 CEST | 11:00 EDT | 08:00 PDT
The multi-attribute method (MAM) is a powerful approach to monitoring critical quality attributes (CQAs) and detecting product variants in a single, streamlined biopharmaceutical workflow. However, widespread adoption in QC has been limited by method complexity, high costs, and operational burden.
Join Prof. Jared Auclair of Northeastern University and Melissa Sato of Agilent Technologies in this SelectScience® webinar as they present a practical path forward – the Agilent MAM.
The Agilent MAM solution addresses these challenges by combining purpose-built Agilent MAM for OpenLab CDS software with robust, highly efficient Agilent LC/MS systems, enabling the confident transition of MAM from R&D into regulated QC environments. Designed according to USP <1060>, this comprehensive solution includes software, LC/MS instrumentation, consumables, and built-in system performance checks to simplify QC method implementation, reduce training requirements, and improve QC turnaround time.
Certificate of attendance
If you attend the live webinar, you will automatically receive a certificate of attendance, including a learning outcomes summary, for continuing education purposes. If you view the on-demand webinar, you can request a certificate of attendance by emailing editor@selectscience.net.
Webinar details
- Cost: Free to attend
- Location: Online
- Duration: 60 minutes
Registration is required to secure your place. If you register but can’t attend live, you will receive a link to the on‑demand recording once it becomes available.
TechTalk: Reliable biopharma QC starts with MAM system readiness
Friday, September 18 at 16:30 BST | 17:30 CEST | 11:30 EDT | 08:30 PDT
Reliable Multi-Attribute Method (MAM) analysis starts with confidence in LC/MS system performance. In GMP-regulated environments, even small changes in system behavior can impact the accurate monitoring of critical quality attributes, making system readiness a critical component of successful MAM workflows.
In this SelectScience® TechTalk, Dr. Mahsan Miladi, an expert in LC/MS workflows for biopharmaceutical characterization and MAM applications, will demonstrate how an automated system readiness workflow can help scientists assess performance, troubleshoot issues faster, and gain confidence in critical analytical results. Using MAM for OpenLab CDS, attendees will see how automated feature extraction, grouping, and predefined acceptance criteria can deliver an objective pass/fail assessment of system readiness from a single injection.
Powered by a purpose-designed 13-peptide standard, the workflow is designed to probe common LC/MS system stressors, from oxidation and metal-adduct formation to mass accuracy and chromatographic resolution challenges. Discover how this automated evaluation of predefined diagnostic targets enables objective assessment of system readiness and helps identify potential sources of performance variation in MAM analyses within GMP-regulated environments.
Certificate of attendance
If you attend the live TechTalk, you will automatically receive a certificate of attendance, including a learning outcomes summary, for continuing education purposes. If you view the on-demand TechTalk, you can request a certificate of attendance by emailing editor@selectscience.net.
TechTalk details
- Cost: Free to attend
- Location: Online
- Duration: 20 minutes
Registration is required to secure your place. If you register but can’t attend live, you will receive a link to the on-demand recording once it becomes available.
