Thermo Scientific™ MAbPac™ RP LC Columns by Thermo Fisher Scientific

Manufacturer Thermo Fisher Scientific  |   Model: IQLAALGABXFAITMBBM  |  Available Worldwide
5.0
/
5.0
  |  1 reviews
Use the new Thermo Scientific™ MAbPac™ RP columns for high-performance reversed-phase (RP) HPLC and LC/MS characterization of monoclonal antibodies (mAbs), fragments, variants, antibody drug conjugates (ADCs), PEGylated proteins, and bispecific proteins. These columns have excellent resolution, long column lifetime, and low carry-over. The surface chemistry, particle size, and pore size, have been optimized to for high resolution separations. Compatible with organic solvent used in H... Read more


Thermo Scientific™ MAbPac™ RP LC Columns by Thermo Fisher Scientific product image
Thermo Scientific™ MAbPac™ RP LC Columns
Request Pricing

Receive your quote directly from the manufacturer.




Average Rating: 5.0
1 Scientist has reviewed this product

5 out of 5
Ease of use
5 out of 5
After sales service
5 out of 5
Value for money


  • Status:

    Reviewer
  • Member since: 2021

  • Organization: Umcu



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Share this Review on LinkedinShare this Review on TwitterShare this Review on Facebook
Best tested RP column for mAb fragments separation
Rating: 5.0

  • Application Area: Separation of mAb fragments

"Column resolution is excellent. After conditioning with 0.5%TFA the column can be used without TFA in the mobile phase thus improving MS ionisation. Use a shallow gradient ranging from 20 to 40% organic over a wide run time 30min to achieve ideal separation of mAb fragments."

Review date: 10 Nov 2021 | Thermo Scientific™ MAbPac™ RP LC Columns

Use the new Thermo Scientific™ MAbPac™ RP columns for high-performance reversed-phase (RP) HPLC and LC/MS characterization of monoclonal antibodies (mAbs), fragments, variants, antibody drug conjugates (ADCs), PEGylated proteins, and bispecific proteins. These columns have excellent resolution, long column lifetime, and low carry-over. The surface chemistry, particle size, and pore size, have been optimized to for high resolution separations.

Compatible with organic solvent used in HPLC and MS under RP conditions

  • Resin is based on a hydrophobic supermacroporous 4µm polymer particles
  • Stable at extreme pH (0 to 14) and high temperature (up to 110 °C)


Efficient with low carry over

  • 1,500 Å large pore size polymeric resin;
  • Efficient separation of protein molecules with very low carry over


Designed for reversed-phase biomolecule LC and LC/MS separations

  • Superior resolution power for monoclonal antibodies and related substances
  • High efficiency with low carry-over
  • Excellent MS compatibility
  • Wide operating pH range: 0 to 14
  • High temperature stability: up to 110 °C
  • High throughput