Opera Phenix High Content Screening System by PerkinElmer, Inc.
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Status:
Reviewer
Member since: 2021
Organization: GSK
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- Ease of use
- After sales service
- Value for money
Crucial for drug discovery and HCA.
Application Area: High content imaging
"Excellent for canned HCA with excellent resolution."
Review date: 08 Apr 2021 | Opera Phenix High Content Screening System
Status:
Advanced Reviewer Member since: 2016
Organization: Purdue University
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- Ease of use
- After sales service
- Value for money
Great instrument, proud to have it.
Application Area:Phenotypic assays and screens
"It is a very powerful high content screening system, offering high speed and high resolution analysis. It is the only HCS system that can use water lenses. It can be configured with up to 4 cameras, which enables high speed and bleed through between channels. The software is intuitive and easy to learn. The price is relatively high but given the unique features, it may be worth the money."
Review date: 19 May 2020 | Opera Phenix High Content Screening System
Status:
Reviewer Member since: 2017
Organization: University College London
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- Ease of use
- After sales service
- Value for money
Great instrument, I can't live without it!
Application Area:High-content screening, confocal image acquisition
"Very high quality confocal microscopic images can be acquired."
Review date: 08 May 2019 | Opera Phenix High Content Screening System
With the Opera Phenix High Content Screening System, simultaneous multicolor confocal image acquisition delivers speed without compromising sensitivity, because spectral crosstalk is reduced to a minimum. That means higher throughput than ever – and richer content, too. Making it the ideal high content screening system for discriminating phenotypes and studying complex disease models, such as primary cells and microtissues.
The Opera Phenix HCS system's innovative optical design lets you generate richer information through extremely sensitive confocal imaging and at higher throughput than ever through simultaneous acquisition – without the issue of crosstalk.
Featured at PerkinElmer AACR 2014.
Opera Phenix High Content Screening System Features:
- Up to four large format sCMOS cameras with simultaneous acquisition in up to four channels, so you can generate images of exceptional quality - faster than ever
- Custom-designed high NA water immersion objectives to capture more photons and provide high image resolution even in thick samples
- Large field of view – 290% larger than the original Opera HCS system to acquire more cells in a single image for robust assay statistics
- State-of-the-art sCMOS image sensors deliver low signal-to-background noise, a wide dynamic range and high resolution – ideal for sensitive and quantitative measurements at short exposure times
- Spinning microlens disk with increased pinhole-to-pinhole distance to further reduce out-of-focus noise in thick samples such as microtissues
- Spinning disk optics and precise synchronization of the excitation laser and camera to minimize phototoxicity and bleaching for live cell assays
- Widefield or confocal imaging modes depending on your assay requirements
- Fast laser-based autofocus to ensure sharp confocal images from every field
- Modular design to adapt the system to your changing application needs – choose from single, dual or four camera configuration with four solid state lasers or a five laser system optimized for FRET applications
Applications:
- Fixed-cell assays
- Live-cell assays
- Complex cellular models
- Protein-protein interactions
- High-throughput phenotyping
Product Overview
