Products & ReviewSpectroscopy

Stunner AF

Stunner AF adds fluorescence detection to plate-based, high-throughput rotating angle dynamic light scattering (DLS) and UV/Vis absorbance measurements from 2 µL on up to 96 samples. Combine all three technologies to measure LNP size, encapsulation efficiency (EE%), and particle concentration data in one experiment. Pivot and pair up UV/Vis and DLS to quantify and size proteins, ADCs, peptides – just like Stunner.

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  • Size & polydispersity: See whether your LNP’s diameter is what you expect and how uniform it is — critical for screening, formulation, and QC.​
  • Encapsulation efficiency: Combine free RNA quantification from fluorescence and total RNA quantification from UV/Vis to make EE% characterization extra easy, detergent-free, and ready for high-throughput.
  • Particle concentration: Sum up the total number of LNPs present in your samples to compare LNP production from one condition or batch to any other.
  • Aggregate detection: RADLS is the most sensitive way to pick up on unwanted particles and samples that have gone south, so you can fix issues fast.​
  • Conjugate characterization: See how much protein is along for the ride by quantifying protein concentration at the same time you’re characterizing your LNP.

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