Assessment of Cellular Phenotypic Changes during Viral Infection using High Content Screening
26 Apr 2016
Dr. Krishna Kota, from United States Army Medical Research, is continually researching highly pathogenic viruses and bacteria to find suitable therapeutics. He uses PerkinElmer’s Opera Phenix High Content Screening System to aid his work in understanding the disease and the pathways in which the virus is modulating. Using this system enables him to observe phenotypic changes in cells thanks to Opera Phenix’s high resolution images and confocal nature, supporting the discovery of small molecules that could eventually lead to drug candidates. Dr. Krishna Kota also discusses the importance of the Colombus Image Data Storage and Analysis System and the High Content Profiler in analysing multiple parameters which are present where viral infection is being monitored.
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Opera Phenix High Content Screening System
RevvityThe Opera Phenix ® Plus High-Content Screening System is the premier confocal solution for today' most demanding high content applications. Drawing on over a decade of experience with the industry-leading Opera ® and Opera ® Phenix system, the Opera Phenix Plus is designed for high-throughput high-content assays, phenotypic screening, assays using complex disease models, such as live cells, primary cells and microtissues, and fast-response assays, such as Ca2+ flux.