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EM ICE High Pressure Freezer

High-pressure freezing with the possibility of light and electrical stimulation

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Average Rating 4.0

Application Area:

Electron microscopy

High-pressure-freezing for sample preparation of biological samples. The EM ICE wokrs fine, it is designed to be used for mass production. However, the price is high, including consumables. Service is OK.

Review Date: 2 Feb 2021 | Leica Microsystems Europe

High-pressure freezing is key for the study of intricate changes in fine structure or cellular dynamics

Currently cryo-fixation is the only way to fix cellular constituents without introducing significant structural alterations. With the Leica EM ICE, cryo-immobilize your aqueous samples under high pressure with a unique freezing principle and uncover secrets of the cellular process.

The EM ICE solution uses a unique, alcohol-free freezing principle to allow a superior cryo-fixation of the specimen enabling better quality results to be obtained:

  • No alcohol in the chamber leads to a faster pressure increase and immediate cooling of the specimen
  • No alcohol residue on the carrier or the specimen
  • Precisely define the timing for light and electrical stimulation
  • Capture and resolve highly dynamic processes at the nanometer scale with millisecond precision.

The EM ICE solution, combining superior high pressure freezing with the possibility of light and electrical stimulation, is the platform for your discoveries.

Brochures

Product brochuresLife Sciences

EM workflow solutions for life science research

Concentrating on workflow solutions, Leica Microsystems provide a product range aligned to your needs in TEM, SEM, LM, and AFM investigations. This 26-page workflow booklet is a compilation of appropriate workflows for the most frequently used electron microscopy (EM) sample preparation methods.


White PapersLife Sciences

Comparing high pressure freezing principles

This white paper, from Leica Microsystems, offers a short comparison of two high pressure freezing principles and shows the advantages of the pneumatic freezing principle of the Leica EM ICE High Pressure Freezer.

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