Fetal Bovine Serum (FBS), also known as Fetal Calf Serum (FCS), is the most widely used growth supplement for cell culture media due to its high content of embryonic growth-promoting factors.
Biological Industries’ FBS reagents undergo the most stringent quality control screening and validation standards to ensure high quality and consistent batches with minimal variability. All of BI’s FBS reagents meet and exceed approved compliance validation specifications. All sera undergo a methodical and comprehensive list of physicochemical, microbiological, and biological performance testing procedures. Each batch of FBS is fully documented and traceable from the source of origin to final filtration, and is traceability certified by the International Serum Industry Association (ISIA). All documentation is available upon request. When growing ES cells, one of the most important parameters is the maintenance of the cells in the undifferentiated state. Pre-screening of the serum is essential before using it for the culture of ES cells. Various lots of sera are screened for the growth of Human ES cells using MEF's as a feeder layer.
The following parameters are measured for the screening: