Strata-X-Drug Solid Phase Extraction

This product guide presents the analytical options for your laboratory's cannabis testing needs on offer from Phenomenex.

Pentachlorophenol (PCP) is a toxic substance, identified as an endocrine disruptor. It exists in the environment due to its wide use as an insecticide, pesticide, and wood preservative. Additionally, it can also be formed from phenol and chlorine during the disinfection process of drinking water. In this application note, researchers utilized a simple solid phase extraction (SPE) method to clean up the groundwater sample, to isolate low-level pentachlorophenol using Strata-X polymeric SPE. A high-efficiency Kinetex 2.6 µm Polar C18 core-shell HPLC/UHPLC column was utilized for analysis, due to its enhanced polar retention.

This application note sets out the challenges and preparation steps for drug detection in alternative matrices such as hair and oral fluids, simplifying methods development for performing LC-MS/MS separations for these samples.

The world is changing and we need to widen our Environmental Scope. Although analytical techniques and established regulated methods are not easily changed; more complex targets, larger lists, and a variety of sample matrices create a daily challenge for environmental chemists. By using the latest technologies and techniques in HPLC/ UHPLC and Sample Preparation, laboratories and chemists are able to develop better approaches to make their work Faster, Cheaper and Easier. Phenomenex is committed to supporting the industry through a comprehensive product portfolio of Sample Preparation, HPLC/UHPLC, and LC-MS, columns and accessories, along with application and method development services to meet industry needs.

This clinical notebook contains a variety of 36 application notes, covering topics in endocrinology and biomarker research, therapeutic drug monitoring, toxicology and sample preparation.

Drug testing in oral fluid has steadily gained popularity over other sample types such as urine and whole blood. One reason for this popularity is the easy non-intrusive sample collection procedure. Oral fluid collection devices often contain a device buffer, to prevent bacterial growth and increase the analytes stability during the sample transit to testing laboratories, but they may cause problems when performing LC/MS analyses. This application note presents a sample preparation procedure to significantly reduce the effects of the device buffer solution while maintaining a reproducible and consistent recovery of analytes.

Use of oral fluid as a drug testing matrix has steadily gained popularity due to its easy and non-intrusive sample collection procedure. The oral fluid collection device provides a buffer solution that contains a number of antibacterial agents and surfactants which acts to prevent bacterial growth and increase the analytes stability during the sample transit to testing laboratories. Presented is a fast sample preparation procedure to reduce detrimental effect of excipients present in the buffer solution of the device.

This application note gives a complete and comprehensive guide to developing your SPE method, including choosing a sorbent, pre-treatment of the sample, general starting methods for Strata-X and for Strata, industry applications and ordering information.

This application note provides guidance on selecting a sample preparation technique for food testing and examples of experiments that use the techniques, which include QuEChERS, Simplified Liquid Extraction and Solid Phase Extraction. The article also includes ordering information for the required Phenomenex products.

This application note provides guidance on selecting a sample preparation technique for environmental testing and a protocol for how to carry out the techniques, which includes QuEChERS, Silica-based and Polymer-based Solid Phase Extraction. The article also includes ordering information for the required Phenomenex products.

In this video Phenomenex showcase the Kinetex C8 and XB-C18 HPLC columns. Kinetex core shell particles allow users to achieve UPLC like efficiencies without the added costs. Kinetex also save run time, save solvent, improve separations and decrease analysis time. Phenomenex also discuss Strata-X-Drug B, a specially designed polymeric SPE sorbent for drugs of abuse analysis and Zebron ZB-1XT for simulated distillation of heavy petroleum products to characterize incoming fuel sources.

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