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SecurityGuard™ ULTRA Guard Cartridge System for UHPLC Columns

SecurityGuard ULTRA offers a convenient and economical way to extend core-shell, sub-2µm, and other UHPLC column lifetimes SecurityGuard™ ULTRA dramatically extends UHPLC column lifetime and is ideal for virtually any manufacturer's UHPLC, sub-2µm or core-shell columns. SecurityGuard ULTRA protects against the damaging effects of chemical contaminants and microparticulates introduced by the sample, mobile phase or system, whic…

Phenomenex Inc

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Reviews

Average Rating 4.9

|3Scientists have reviewed this product

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Stable in our laboratory

 

Average Rating 5.0

Application Area:

Analysis of OTC products

Reproducible, clean chromatography. These guard cartridges are a stable in our lab. Every LC column we have, has this guard cartridge attached. Phenomenex customer service is exceptional. They care about the end user, and they do everything they can to help with any questions or issues.

Review Date: 23 Mar 2023 | Phenomenex Inc

Great performance.

 

Average Rating 5.0

Application Area:

UHPLC

It is easy to use with low dead volume. It extended the column life twice.

Review Date: 18 Jun 2021 | Phenomenex Inc

Great product.

 

Average Rating 4.7

Application Area:

UHPLC analysis of Environmental samples

I used the Security Guard cartridge for the analysis of environmental samples. Although we performed thorough sample preparation and filtration, our sample analysis still shows a number of artifact peaks at the lower levels. With the Security Guard cartridge, we realise that this could reduce the presence of the artifact peaks that is possibly due to impurities that remains in the final sample. Each guard cartridge could last for about 300 sample injections before we need to replace them., and it's easy to fit onto any HPLC columns.

Review Date: 24 Aug 2016 | Phenomenex Inc

SecurityGuard ULTRA offers a convenient and economical way to extend core-shell, sub-2µm, and other UHPLC column lifetimes SecurityGuard™ ULTRA dramatically extends UHPLC column lifetime and is ideal for virtually any manufacturer's UHPLC, sub-2µm or core-shell columns. SecurityGuard ULTRA protects against the damaging effects of chemical contaminants and microparticulates introduced by the sample, mobile phase or system, which can negatively impact column lifetime, method sensitivity, quantitation and peak identification. By reducing the frequency of column replacements, as well as the need for troubleshooting and system down time, SecurityGuard ULTRA saves chromatographers time and money. Pressure-rated up to 20,000 psi (1,378 bar), these guard cartridges have no significant impact on chromatography, backpressure or dead volume. To watch how easy it is to install SecurityGuard ULTRA visit the product webpage. SecurityGuard ULTRA provides the following advantages: Virtually no change in chromatography Easy cartridge replacement Universal fit compatible with majority of UHPLC column endfittings Pressure rated up to 20,000 psi. Phenomenex also offers an interactive web application where users can enter their UHPLC, sub-2µm or core-shell column information to find the most appropriate column protection system. Visit the interactive selection tool at www.phenomenex.com/guardit

Brochures

Application NoteSeparations

The ultimate guide to HPLC/UHPLC: Reversed phase selectivity

In this step-by-step selectivity guide, Phenomenex provides an easy overview of the reversed phase HPLC/UHPLC options available to you. Download to understand the differences between the columns available, and select the right solution for your specific method and goals.


Application NoteSeparations

LC-MS/MS Environmental Applications

The world is changing and we need to widen our Environmental Scope. Although analytical techniques and established regulated methods are not easily changed; more complex targets, larger lists, and a variety of sample matrices create a daily challenge for environmental chemists. By using the latest technologies and techniques in HPLC/ UHPLC and Sample Preparation, laboratories and chemists are able to develop better approaches to make their work Faster, Cheaper and Easier. Phenomenex is committed to supporting the industry through a comprehensive product portfolio of Sample Preparation, HPLC/UHPLC, and LC-MS, columns and accessories, along with application and method development services to meet industry needs.


Application NoteSeparations

Clinical Sample Preparation Guide

This application note discusses sample preparation techniques for a variety of clinical samples for simplified liquid extractions (SLE) and solid phase extraction (SPE).



Application NoteSeparations

A Rapid and Robust Sample Preparation Method for Quantitation of Nicotine from Oral Fluid

Nicotine, its metabolite cotinine, and anabasine, a tobacco alkaloid, are often used to detect tobacco exposure. For tests like this, oral fluid collection has emerged as an alternative to other biological matrices. The additives and preservative buffer (critical for preservation of the chemical integrity of the oral fluid sample) present in the collection devices, must be removed for the proper upkeep of the mass spec detector. This technical note presents a solid phase extraction (SPE) method for simultaneous detection and quantitation of nicotine, cotinine, and anabasine from oral fluid.


Application NoteSeparations

UHPLC Column Protection Dramatically Extends UHPLC Column Performance and Lifetime

The greatest concern when using UHPLC columns is protecting the column from the damaging effects of microparticulates and sample contaminants. This application note describes how an ultra-high performance column protection system, specifically designed for UHPLC systems using sub-2 μm and core-shell, can protect the UHPLC column, extending its lifetime and saving money, while minimizing system troubleshooting and downtime.


Application NoteSeparations

UHPLC Column and System Protection Essentials

This application note provides information on how you can protect your UHPLC instrument and columns by investing in high-quality vials, UHPLC guards and by using filtered samples and mobile phases that will deliver optimal performance. The article provides guidance on selection of UHPLC accessories and ordering information.


Application NoteSeparations

UHPLC Column Protection Dramatically Extends UHPLC Column Performance and Lifetime

UHPLC columns can significantly improve chromatographic separations, but they also present unique challenges. Once the UHPLC system components are optimized, perhaps your greatest concern is protecting the column from the damaging effects of microparticulates and sample contaminants. An ultra-high performance column protection system, specifically designed for UHPLC systems using sub-2 μm and core-shell particle columns, can be used to extend column lifetime (saving both money and time through less frequent column replacement), while minimizing system troubleshooting and downtime.

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