ResourceSeparations
Clinical Sample Preparation Guide
18 Oct 2017This application note discusses sample preparation techniques for a variety of clinical samples for simplified liquid extractions (SLE) and solid phase extraction (SPE).
This application note discusses sample preparation techniques for a variety of clinical samples for simplified liquid extractions (SLE) and solid phase extraction (SPE).
Unique, 100 % aqueous stable mixed-mode phase that provides both polar and non-polar retention. The surface contains a positive charged ligand which aids in the retention of acidic compounds through ionic interactions, while the C18 ligand promotes general reversed phase retention. The positively charged surface also improves basic compound peaks shape through ionic repulsion. Available in: 1.6µm, 3µm, and 5µm
100 % aqueous stability and enhanced selectivity/retention for polar analytes without diminishing useful non-polar retention.
Rugged C18 with focus on strong hydrophobic retention of non-polar and polar compounds.
Positive pressure 96-well plate sample processing with Presston 1000 offers an advanced alternative to traditional vacuum manifold processing. To offer a wider applicability, Presston 1000 is equipped for processing samples in both a low pressure setting for typical solid phase extraction steps and a high pressure setting for very viscous sample processing and for sample dry down. In addition, Presston 1000 is compatible with standard 96-well plates, microelution plates, and 1 mL tubes with the addition of a tabless tube holder.
Used under HILIC running conditions, this phase provides the highest polar selectivity for retention and separation of hydrophilic compounds.
100% aqueous stable reversed phase chemistry with hydrophobic, aromatic, and enhanced polar selectivity.
Moderate hydrophobic and steric selectivity is offered, bringing ultra-high performance to USP L7 and other octyl silane methods.
Balanced C18 phase that provides the highest degree of hydrophobic selectivity relative to the other Kinetex phases.
Novel pH 1-12 stable C18 that delivers robust methods and improved peak shape for bases.
β-Gone β-Glucuronidase Removal 96-well plates and tubes are designed to target and remove β-glucuronidase from hydrolyzed urine samples without requiring additional time or method development. In a single step and in less than 1 minute, your hydrolyzed samples are ready for analysis. In Under a Minute You Can Easily: Increase HPLC/UHPLC Column Lifetime Reduce Mass Spec Maintenance Maintain the Selectivity of Your HPLC/UHPLC Column
Robust, Accurate Polymeric Solid Phase Extraction (SPE) Products
Simplify Your Liquid-Liquid Extractions with Faster, Easier, and More Reliable SLE
SecurityGuard ULTRA offers a convenient and economical way to extend core-shell, sub-2µm, and other UHPLC column lifetimes SecurityGuard™ ULTRA dramatically extends UHPLC column lifetime and is ideal for virtually any manufacturer's UHPLC, sub-2µm or core-shell columns. SecurityGuard ULTRA protects against the damaging effects of chemical contaminants and microparticulates introduced by the sample, mobile phase or system, which can negatively impact column lifetime, method sensitivity, quantitation and peak identification. By reducing the frequency of column replacements, as well as the need for troubleshooting and system down time, SecurityGuard ULTRA saves chromatographers time and money. Pressure-rated up to 20,000 psi (1,378 bar), these guard cartridges have no significant impact on chromatography, backpressure or dead volume. To watch how easy it is to install SecurityGuard ULTRA visit the product webpage. SecurityGuard ULTRA provides the following advantages: Virtually no change in chromatography Easy cartridge replacement Universal fit compatible with majority of UHPLC column endfittings Pressure rated up to 20,000 psi. Phenomenex also offers an interactive web application where users can enter their UHPLC, sub-2µm or core-shell column information to find the most appropriate column protection system. Visit the interactive selection tool at www.phenomenex.com/guardit
Available retention mechanisms include reversed phase, ion exchange, normal phase and mixed mode
