Kinetex C18
Balanced C18 phase that provides the highest degree of hydrophobic selectivity relative to the other Kinetex phases.
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Outstanding separations no matter the conditions.
Analytical
Kinetex columns are quite useful for antioxidizing agents such as BHA, BHT, Ethoxiquin and others. Even with drastic changes, separations are very good.
Review Date: 11 Apr 2024 | Phenomenex Inc
Superb performance and fabulous reproducibility
Efficient separation of plant metabolites
Kintex columns are capable of separating plant metabolites with great sensitivity and better resolution. We usually get reproducible results.
Review Date: 28 Sept 2022 | Phenomenex Inc
Robust columns!
Analyze cosmetic products
These columns are robust and last for years as long as you take good care of them. The validation kits are great because they come with different batches of the same column which is perfect for method validation testing.
Review Date: 26 Sept 2022 | Phenomenex Inc
Great column
Pharmaceutical product analysis
A well made, easy to maintain column that produces consistent results.
Review Date: 21 Jan 2022 | Phenomenex Inc
Reproducible resutls, Less column conditioning required and robust.
Bioanalysis
Results obtained are reproducible from batch to batch of column. Robust column with great price.
Review Date: 7 Jun 2021 | Phenomenex Inc
Great results.
C18
We used it for method development for drug development all the time. Our go to.
Review Date: 3 Mar 2021 | Phenomenex Inc
Afforable and very accessible.
Lipid separation via HPLC
A product that gives very clean data and is very reproducible. The lifetime of the product is very good. Product is afforable and very accessible.
Review Date: 6 Mar 2020 | Phenomenex Inc
Good robust column for my samples of interest.
Pesticides
I used this column for method development for pesticides in juice samples. Good peak shapes and chromatographic profiles for most of my peaks of interest even when matrix effects are present in the samples. Good lifetime and column robustness as well.
Review Date: 4 Dec 2017 | Phenomenex Inc
- pH Range: 1.5-8.5 (1.5-10 under isocratic conditions)
- USP Classification: L1
- Effective Carbon Load: 12%
Brochures
Popular LC Columns for Clinical Research
This product brochure provides a comprehensive overview of the wide range HPLC and UHPLC options available from Phenomenex, with recommendations for column and phase based on applications such as drug research panels, bile acid, and 25-OH vitamin D analysis.
Phenomenex Core-Shell Technology: These Phases ROCK Your LC Laboratory
In this brochure, discover how Core-Shell technology can enhance your chromatography no matter what industry you work in.
Column chemistry considerations for full coverage of PFAS analyte ranges
Download this application note to find things to consider when choosing a column for full coverage of PFAS analytes.
Allowable Adjustments to European Pharmacopoeia (Ph. Eur.) Methods
The European Pharmacopoeia (Ph. Eur.), of the Council of Europe is a pharmacopoeia, listing a wide range of active substances and excipients used to prepare pharmaceutical products in Europe. It includes general and specific monographs that give quality standards for all the main medicines used in Europe. All medicines sold in the 38 Member States of the European Pharmacopoeia must comply with these quality standards so that consumers have a guarantee for products obtained from pharmacies and other legal suppliers. It is widely understood that all HPLC packings are not alike, and no single column can perform a myriad of desired separations. HPLC packings differ in hydrophobicity, surface coverage, surface area, pore size, and particle shape. In this application note, find out which column is right for you.
Allowable Adjustments to United States Pharmacopoeia (USP) Methods
It is widely understood that all HPLC packings are not alike, and no single column can perform a myriad of desired separations. HPLC packings differ in hydrophobicity, surface coverage, surface area, pore size, and particle shape. In this application note, find out which column is right for you according to the USP Listings.
Separation of clavulanate and amoxicillin using the Kinetex 5 µm C18 column and under USP allowable adjustments
In this application note, Phenomenex presents the related substances test of the USP monograph which outlines the separation of all relevant impurities from clavulanate potassium. This method was studied and improvements were made to provide higher resolution (Rs) and a faster separation time within allowable adjustments.
Separation of lovastatin and related impurities with the Kinetex 5 µm C18 column and under USP allowable adjustments
In this application note, Pheneomenex presents the related substances test of the USP monograph which outlines the separation of all relevant impurities from lovastatin. This method was studied and improvements were made to provide higher resolution (Rs) and a faster separation time within allowable adjustments.
Separation of ibuprofen and valerophenone using the Kinetex 5 µm C18 column and under USP allowable adjustments
The related substances test of the USP monograph outlines the separation of all relevant impurities from ibuprofen. In this application note, this method was studied and improvements were made to provide higher resolution (Rs) and a faster separation time within allowable adjustments.
Robust separation of hydroxychloroquine and chloroquine in hydroxychloroquine sulfate tablets using the Kinetex 5 µm C18
In this application note, Phenomenex compares two particle morphologies of similar L1 (C18) phase in the separation of hydroxychloroquine and related impurity chloroquine under the USP conditions for assay of hydroxychloroquine sulfate tablets. The application note demonstrates the potential method improvements that can be achieved per the allowable adjustments outlined in USP General Chapter <621> relative to the original column and conditions referenced in the monograph.
Robust separation of hydrochlorothiazide and chlorothiazide in hydrochlorothiazide tablets using the Kinetex 5 µm C18 column
In this application note, Phenomenex highlights the robust and reproducible separation of hydrochlorothiazide and its related impurity chlorothiazide under the USP monograph conditions for assay of hydrochlorothiazide tablets.
Limit of free salicylic acid in aspirin tablets using the Kinetex 5 µm C18 under USP allowable adjustments
In this application note, Phenomenex presents the robust separation of aspirin (acetylsalicylic acid) and related impurity salicylic acid under the USP conditions. The application note demonstrates the potential method improvements that can be achieved per the allowable adjustments outlined in USP General Chapter <621> relative to the original column and conditions referenced in the monograph.
HPLC Analysis of 22 Common Antibiotics Using a Kinetex PS C18 Column
In this application note, 22 common antibiotics are analyzed to demonstrate the Kinetex PS C18 HPLC/UHPLC column's unique multi-modal selectivity and improved chromatographic performance for polar bases.
HPLC and UHPLC reversed-phase method development - Selecting a reproducible starting point
Watch this on-demand webinar to learn more about method development optimization for reversed-phase chromatography
