ResourceSeparations
Phenomenex Core-Shell Technology: These Phases ROCK Your LC Laboratory
3 May 2017In this brochure, discover how Core-Shell technology can enhance your chromatography no matter what industry you work in.
In this brochure, discover how Core-Shell technology can enhance your chromatography no matter what industry you work in.
Used under HILIC running conditions, this phase provides the highest polar selectivity for retention and separation of hydrophilic compounds.
Highly reproducible pentafluorophenyl phase exception for halogenated, conjugated, isomeric, or highly polar compounds.
Aromatic and moderate hydrophobic selectivity result in the great retention and separation of aromatic hydrocarbons.
100% aqueous stable reversed phase chemistry with hydrophobic, aromatic, and enhanced polar selectivity.
Moderate hydrophobic and steric selectivity is offered, bringing ultra-high performance to USP L7 and other octyl silane methods.
Balanced C18 phase that provides the highest degree of hydrophobic selectivity relative to the other Kinetex phases.
This unique C18 phase yields increased hydrogen bonding with hydrophobic selectivity, resulting in improved peak shape for basic compounds and increased retention of acidic compounds.
Novel pH 1-12 stable C18 that delivers robust methods and improved peak shape for bases.
Works for desalting and clean up of biological samples
Purification and Analysis of Synthetic OligonucleotidesThe Clarity BioSolutions LC portfolio includes novel RP-LC and IEX-LC columns for purifying and characterizing synthetic DNA / RNA used in biological research, therapeutic development, and biochemical manufacturing.Clarity Oligo-MS™: LC/MS analysisClarity Oligo-RP™: RP-LC purification and analysisClarity Oligo-WAX™: IEX-LC purification
Easily separate N-1 failure sequences from target oligo with > 90% purities
Core-Shell Particles Precision Engineered for Protein and Peptide Separations. Core-shell particle technology provides striking increases in peak capacity and resolution at lower backpressure, giving chromatographers the ability to achieve ultra-high performance on ANY system, HPLC or UHPLC. A uniform porous silica layer is grown around a solid, spherical silica core, providing effective retention and selectivity with improved resolution, speed, and recovery. Next, optimizing the pore size and shell thickness for intact proteins or smaller peptide fragments provides well-defined depth penetration of biomolecules leading to maximum separation power. Column Specifications: Phase: PEPTIDE XB-C18, WIDEPORE C4, WIDEPORE XB-C18, WIDEPORE XB-C8 Particle Size: 1.7, 2.6, 3.6, 5.0 µm Pore Size: 200, 100 Å Length: 50, 100, 150, 250 mm ID: 2.1, 3.0, 4.6, 10.0, 21.2 PEPTIDE XB-C18 Synthetic peptide impurity analysis Peptide mapping Identifying protein modifications - Glycosylation - Substitution - Truncation Analyzing post-translational modifications - Deamidation - Oxidation - Deletions WIDEPORE XB-C18 Proteins Hydrophilic proteins PEGylated proteins High temperature separations Alternative selectivity for peptide mapping WIDEPORE XB-C8 Large proteins Moderately hydrophobic proteins Monoclonal antibodies Glycosylated proteins High temperature separations WIDEPORE C4 Very large proteins Very hydrophobic proteins Membrane proteins Least retentive
