NovoCyte Flow Cytometer
NovoCyte is a high-performance benchtop flow cytometer designed for all levels of users and all types of laboratories. The budget-friendly instrument can detect up to 17 parameters with enhanced sensitivity and resolution. The customizable laser and optical configurations of the NovoCyte offer a high degree of flexibility while providing complex cell analysis capabilities. The NovoExpress software facilitates easy and intui…
Definitely recommend its purchase. Versatile, easy to use, and maintain.
Identification and counting of iPSC's
Definitely recommend its purchase. The instrument was easy to use. The on-site training was informative. I wish a few training webinars had been provided on using the instrument prior to the on-site training. A lot of versatility is available for cell identification with the lasers and filters that can be installed. I think this instrument will be very useful for the research we are doing. Maintenance procedures are preprogrammed. Quality control sample lasts for a long period, simple to prepare and perform.
Review Date: 9 Dec 2024 | Agilent Technologies
The top value of machine and lifesaver of pre/post services
Immunoassays
As an R&D scientist in Cell Therapy filed, I need to perform vast amounts of Immunoassays. The NovoCyte Benchtop Flow Cytometer from Agilent Technologies is a lifesaver with high-throughput and reliable reproducibility! In addition to the very user-friendly equipment application, I am always impressed by their Craftsman’s SPIRIT and pre/post services! Following our Regional Sales Specialist Vladi Cherepakhin's instructions, we have never gotten any issues with the machines since 2019.
Review Date: 17 Dec 2022 | Agilent Technologies
Easy to use instrument
Flow cytometry
This instrument and its software is easy to use.
Review Date: 27 Sept 2021 | Agilent Technologies
Excellent!
Research
Great value for money.
Review Date: 21 Mar 2021 | Agilent Technologies
Extremely robust, reliable and user friendly.
Analysis of natural killer cell phenotype and function in cancer
This instrument is extremely robust, reliable and user friendly. It is valued by our most experienced researchers and new students alike for its consistency and ease of use. Niga Nawroly goes above and beyond in her training sessions and after sales care. I highly recommend the Novocyte!
Review Date: 19 Jun 2020 | Agilent Technologies
It is very good.
FACS
It is very good.
Review Date: 30 Apr 2019 | Agilent Technologies
It is the most used instruments in our lab. Even undergrads can use the instrument
Life science
Instrument is very very easy to use even for someone new to flow cytometer. Get your data without hassle.
Review Date: 14 Mar 2019 | Agilent Technologies
Good machine - does the job - one of the best value in the marketplace.
Cells and algae
This is a good machine for the money. Very good value.
Review Date: 18 Feb 2019 | Agilent Technologies
Outstanding service. Quality instrument.
Flow cytometry
We consistently received a high level of customer service quality from Heather Paich and the ACEA staff. We recently had an issue with our Novocyte instrument during an important experiment. Heather went above and beyond to help us resolve the problem in a timely manner. Heather’s customer service is unrivaled by any other company representative I have ever worked with in the past. She is extremely knowledgeable and supportive. Heather’s customer service has left quite an impression on our research group, and we would surely recommend ACEA instruments due to our excellent experience.
Review Date: 17 Jan 2019 | Agilent Technologies
We are sohappy to have this apparatus in the lab: reliable and robust!
Immune phenotyping (mouse, human)
Easy to use both for data acquisition and data analysis Calibration allowing results fiability Autosampler for analysis of many samples at the same time (24 tube racks, 96 wells plate) - with a single negative point: no refrigeration of the plate whereas aquisition can be quite long routine care and maintenance easy Very efficient and professional technical & scientific supports, for the apparatus but also for the design of antibody panels
Review Date: 23 Jul 2018 | Agilent Technologies
NovoCyte is a high-performance benchtop flow cytometer designed for all levels of users and all types of laboratories. The budget-friendly instrument can detect up to 17 parameters with enhanced sensitivity and resolution. The customizable laser and optical configurations of the NovoCyte offer a high degree of flexibility while providing complex cell analysis capabilities.
The NovoExpress software facilitates easy and intuitive sample acquisition and analysis. Automation of multiple fluidic functions eliminates cumbersome and time-consuming procedures. Manual sample handling is minimized by the flexible NovoSampler Pro. The system can automatically analyze samples in single tubes, multi-tube racks, or 24-, 48-, or 96-well plates
Rewiring the metabolism of CAR-T cells
Join Professor Mercedes Rincon, University of Colorado Anschutz School of Medicine, as she discusses the groundbreaking advancements in adoptive T cell therapy, particularly chimeric antigen receptor (CAR) T cell therapy. While CAR-T therapy has achieved impressive complete remission rates in 60–90% of patients with relapsed/refractory B-cell acute lymphoblastic leukemia (r/r-B-ALL), challenges such as treatment failures and relapses remain significant obstacles.
Metabolism plays a critical role in T cell function, shaping immune responses. While glycolysis is essential for T cell expansion, it can restrict the self-renewal capacity of CAR-T cells during manufacturing. Mitochondrial respiration is vital for their survival and effectiveness. Recent findings have highlighted MCJ, a protein that negatively regulates mitochondrial function in CD8 cells. Loss of MCJ enhances mitochondrial respiration, cytokine secretion, and anti-tumor activity. Targeting MCJ to boost mitochondrial metabolism presents a promising strategy to enhance the efficacy of CAR-T cells and advance adoptive T cell therapies.
Key learning objectives
- Understand the current landscape of adoptive T-cell therapy
- Explain the role of metabolism in T cell function, highlighting the significance of glycolysis and mitochondrial respiration in enhancing CAR-T cell efficacy
- Identify the potential of MCJ as a therapeutic target to improve mitochondrial metabolism, cytokine secretion, and overall effectiveness of CAR-T cell therapies
Who should attend?
- Researchers and scientists specializing in CAR T-cell therapy, immunotherapy development, cell metabolism, glycolysis, and mitochondrial respiration.
Certificate of attendance
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
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