IonFlux Mercury HT
The most affordable high throughput automated patch clamp on the market
The supplier does not provide quotations for this product through SelectScience. You can search for similar products in our Product Directory.
The IonFlux mercury HT is the world's highest throughput and most economical automated patch clamp instrument designed. The system utilizes Fluxion's Well Plate Microfluidics™ (WPM) to conduct high throughput patch clamp measurements in a convenient and flexible 384-well plate format.
The system is ideal for a wide range of ion channel screens, including voltage- and ligand-gated channels. Typical applications include ion channel drug pharmacology, cardiac safety profiling, and functional expression of ion channels.
IonFlux Mercury HT has a space-saving benchtop footprint and does not require any manual patch clamp technique. This makes it ideal for screening centers and drug discovery labs who want to add ion channel capabilities. The system easily integrates with existing laboratory robotics to create automated workflows.
Cytogenetic Monitoring of Cancer Progression in Circulating Tumor Cells Utilizing the IsoFlux System and GenASIs Spectral Imaging Technology
Fluorescence in situ hybridization (FISH) has emerged as a clinically-useful tool for understanding patient-specific traits of cancer at the molecular level. FISH is typically performed on biopsied tissue samples obtained during surgery. Circulating tumor cells (CTCs) have emerged as a potential source of clinically-useful information that can be accessed with far greater frequency than tissue biopsies. In addition to discussing the current challenges for running FISH on CTCs, this application note presents a complete method for CTC analysis.
Transiently Transfected Cell Lines for GABA Receptor Screening using the IonFlux System
Read this application note which describes an automated patch-clamp assay using transiently
transfected mammalian cells (HEK293T) with the IonFlux instrument (Fluxion Biosciences). The assay was validated by measuring the electrophysiological response of benzodiazepine-based compound HZ166. The use of transiently transfected cells allows for maximum flexibility for the assembly of different GABAA receptor types for screening purposes and the robustness of the developed assay makes it well suited for the high-throughput screening using the IonFlux HT system.
Microfluidics technology provides physiologically relevant cell-based models for high-throughput drug discovery
Jeff Jensen, CEO of Fluxion Biosciences, describes how microfluidics technology fuels advances in drug discovery through physiologically relevant cell-based assays
Fluxion launches a fully packaged ion channel screening solution
A complete system for lead-to-answer screening in ion channel assays
