UHPLC and HPLC > UHPLC and HPLC Columns Products & Reviews

Protein/Peptide Columns

Most chromatographers have experienced problems retaining and separating polar compounds using conventional reversed-phase chromatography.  These difficult-to-analyze compounds either pass through the column unretained or, if retained at all, co-elute at the beginning of the chromatogram.  Waters AtlantisTM columns are designed for these types of challenging separations and are available in two chemistries: dC18 and HILIC sili…

Unleash the power of your laboratory's instrumentation. CORTECS® 1.6 µm and 2.7 µm solid-core columns deliver new levels of performance. CORTECS Columns are available in both reversed-phase and HILIC options, giving you the flexibility and power to develop methods for challenging separations even faster. With different particle characteristics and innovative charged surface modifications, CORTECS Columns are suitable for use…

ACQUITY UPC2 Column Technology for Chiral and Achiral Separations. ACQUITY UPC2 Trefoil™ 2.5 µm Columns are uniquely designed for the ACQUITY UPC2 System. Selectivity and speed for chiral separations Reduce method development time Based on modified polysaccharide-based stationary phases for broad-spectrum chiral selectivity. ACQUITY UPC2 Torus™ Columns simplify the method development process with four completely new…

HILIC for Large Biomolecules.

Size Exclusion Columns.

Oligonucleotide Columns

Reversed-Phase Peptide Columns

Reversed-Phase Peptide Columns

More than just a column - A solution providing application-focused standards, methods, and exclusive support so you can easily and reliably achieve state-of-the-art separations.

Designed for selectivity – improve your ability to separate co-eluting peaks

Universal UHPLC columns

ACQUITY Premier Columns with MaxPeak High-Performance Surface (HPS) technology reduce analyte/surface interactions.

Solving one of the most challenging chromatographic problems, retaining polar compounds

Accelerate early research, development, & release testing of GTx drug substances and products

ACQUITY UPLC® HSS (High Strength Silica) T3 Columns contain the first and only 100% silica particle designed, tested and intended for use in applications up to 15000 psi/1000 bar. The ACQUITY UPLC® HSS particle is not an HPLC particle. High pore volume HPLC particles do not possess the mechanical stability necessary to withstand the high column packing and operating pressures of UPLC® separations. The first ligand chemistry in…

The Atlantis® T3 HPLC columns set the standard for retention and separation of polar compounds via reversed-phase HPLC. Atlantis® T3 columns are a universal, silica-based, reversed-phase C18 line of HPLC columns that not only retain and separate small, water-soluble polar organic compounds, but also provide superior performance across a wider pH range. Atlantis® columns are the culmination of over 30 years of bonded phase rese…

SunFire™ columns feature excellent low pH stability and improved column lifetime compared to many silica-based HPLC column brands. SunFire columns are packed with state-of-the-art silica and new proprietary C18 and C8 bonding and endcapping for high efficiency, resulting in greater sensitivity.  SunFire columns are manufactured to achieve the highest level of chromatographic consistency column-to-column and batch-to-batch. MS-…

ACQUITY UPLC® BEH C18 and C8 columns were designed to be the universal columns of choice for most UPLC® separations by providing the widest pH range.They incorporate trifunctional ligand bonding chemistries which produce superior low pH stability and ultra-low column bleed. This low pH stability is combined with the high pH stability of the 1.7 µm BEH particle to deliver the widest usable pH operating range. In addition, these…

ACQUITY UPLC® BEH Shield RP18 columns combine Waters patented Shield Technology* with BEH Technology™ by incorporating an embedded carbamate group into the bonded phase ligand.Waters shield ligands consistently demonstrate increased retention of phenolic compounds versus straight chain alkyl columns. The alternate selectivity and excellent peak shape from the embedded polar group ligand, when combined with the wide pH range an…

Column-to-column and batch-to batch reproducibility

Used in a wide range of validated methods

Introducing Waters ACQUITY CSH and XSelect Columns - Powered by CSH Technology Waters patent-pending, Charged Surface Hybrid (CSH™) Technology powers the new Waters ACQUITY CSH and XSelect Column families.CSH Technology columns offer separation scientists a wider range of selectivities and greater performance in LC/MS-compatible mobile phases. Waters CSH Technology empowers UPLCand HPLC systems to provide separations with:Wide…

200A pore size;  available in 2.0, 3.0, 3.9, 4.0, 4.6, 10 , 21.2 and 50  mm ids, and lengths from 50 - 250 mm. Pursuit columns are ideal for pharmaceutical applications using LC/MS, from analyzing lead compounds and biological samples in drug discovery, to implementing dependable analysis of raw materials and approved drugs in the QC process.  Build on the large 200A pore size silica, high liquid density delivers up to 40% fas…

200A pore size;  available in 2.0, 4.6, 10and 21.2  mm ids, and lengths from 50 - 250 mm. Pursuit columns are ideal for pharmaceutical applications using LC/MS, from analyzing lead compounds and biological samples in drug discovery, to implementing dependable analysis of raw materials and approved drugs in the QC process.  Build on the large 200A pore size silica, high liquid density delivers up to 40% faster separations witho…