UHPLC and HPLC Columns Products & Reviews

YMC-Triart: Robust and reproducible (U)HPLC columns with a wide range of stability towards pH (1-12), temperature and 100% aqueous eluents.

Coated and immobilized CHIRAL ART polysaccharide columns by YMC offer wide selectivity range, high stability and attractive pricing.

Capillary columns available with every fully porous RP/NP/HILIC phase from YMC for high sensitivity analyses. Compatible with nearly all Nano-/MicroLC/MS systems due to two different connection sizes (1/16" and 1/32").  

Highly robust (U)HPLC columns for BioLC which are stable towards pH and temperature. Different pore sizes are available for the analysis of peptides, proteins, antibodies and oligonucleotides. 

200A pore size;  available in 2.0, 3.0, 3.9, 4.0, 4.6, 10 , 21.2 and 50  mm ids, and lengths from 50 - 250 mm. Pursuit columns are ideal for pharmaceutical applications using LC/MS, from analyzing lead compounds and biological samples in drug discovery, to implementing dependable analysis of raw materials and approved drugs in the QC process.  Build on the large 200A pore size silica, high liquid density delivers up to 40% fas…

200A pore size;  available in 2.0, 4.6, 10and 21.2  mm ids, and lengths from 50 - 250 mm. Pursuit columns are ideal for pharmaceutical applications using LC/MS, from analyzing lead compounds and biological samples in drug discovery, to implementing dependable analysis of raw materials and approved drugs in the QC process.  Build on the large 200A pore size silica, high liquid density delivers up to 40% faster separations witho…

600 bar; superficially porous, 2.7 µm particle6; available in 2.1 - 4.6 mm id;  30 - 150 mm lengths. ZORBAX Eclipse Plus columns feature improved silica, special bonding and optimized endcapping that combine to deliver exceptional peak shapes for a wide range of analytes.   Agilent's Poroshell 120 columns have a solid 1.7 µm core and a porous .5 µm outer layer, for a total 2.7 µm particle that delivers high resolution and high…

600 bar; superficially porous, 2.7 µm particle6; available in 2.1 - 4.6 mm id;  30 - 150 mm lengths. ZORBAX Eclipse Plus columns feature improved silica, special bonding and optimized endcapping that combine to deliver exceptional peak shapes for a wide range of analytes.  Agilent's Poroshell 120 columns have a solid 1.7 µm core and a porous .5 µm outer layer, for a total 2.7 µm particle that delivers high resolution and high…

400 bar; available in 2.1 - 4.6 mm id; 30, 50, 75, 100, 150 mm lengths. Manufactured by Agilent to rigorous QC specifications, the ZORBAX family encompasses 5 particle sizes and more than 32 phases, for reliable scalability and transferability from HPLC to UHPLC, from lab to lab and around the world.

Extend-C18 columns incorporate a unique patented bidentate silane, combined with a double-endcapping process that protects the silica from dissolution at high pH - up to pH 11.5. 

Eclipse Plus columns provide the ultimate in performance for silica-based columns. Peak shape for the Eclipse Plus is excellent for the most challenging basic compounds, improving efficiency and resolution with these sample types. These results are achieved by improvements in the silica manufacturing and bonding technology, which is completely controlled by Agilent. 

Agilent Bio-Monolith Protein A and Protein G LC columns are designed for analytical separation of all IgG subclasses (human and mouse). They deliver fast and accurate quantitation of mAb titer and purification of small amounts of mAb for further characterization.

In order to more easily isolate and identify proteins in human serum, the Agilent Human 14 Multiple Affinity Removal Column is designed to chromatographically remove fourteen interfering high-abundant proteins from human plasma samples.

Agilent Poroshell columns are ideal for fast separations of proteins and peptides because the unique particle allows for fast flow rates to be used while maintaining sharp, efficient peaks. 

Agilent ZORBAX Eclipse XDB columns – C18, C8, Phenyl and CN – provide four bonded phase choices for method development optimization. These columns provide good peak shape over a wide pH range (2–9) for additional method development flexibility with one family of columns. Eclipse XDB columns can be used for method development at low pH (2–3) and the same column can be used for method development in the mid pH (6–8) region.

Poroshell 120 columns provide rugged, high resolution separations within the pressure range of any mainstream LC system, making the benefits of sub-2 µm performance available with all existing LCs.Poroshell columns can achieve high resolution and high speed separations on current instruments, and higher resolution and speeds on new high-pressure LC and LC/MS systems. Stable to 600 bar, Poroshell 120 are great for fast UHPLC an…

The Ultra line represents Restek’s broadest selection of stationary phases on a single silica support. Made of high-purity, type-B silica that minimizes activity and creates high-density bonding, these columns are designed for selective and reliable HPLC applications.The Ultra Aqueous C18 HPLC column provides reproducible retention times and can be used with highly aqueous mobile phases, which may eliminate the need for sample…

Properties: • Increased retention for dipolar, unsaturated, or conjugated solutes • Enhanced selectivity when used with methanolic mobile phase • Ideal for increasing sensitivity and selectivity in LC-MS analyses particle size: 3 μm or 5 μm, spherical pore size: 100 Å carbon load: 15% endcap: fully endcapped pH range: 2.5 to 8 temperature limit: 80 °C USP phase: L11 phase category: phenyl ligand type: unique Biphenyl

The Raptor™ ARC-18 column is made specifically for high-throughput, low–sample prep LC-MS/MS applications. A well-balanced retention profile offers better detection and integration of large, multiclass analyte lists, and steric protection helps this SPP column endure the harsh, low-pH mobile phases needed for mass spec without sacrificing retention or peak quality. Restek chemists became the first to combine the speed of supe…

Restek chemists became the first to combine the speed of superficially porous particles (also known as SPP or “core-shell” particles) with the resolution of highly selective USLC® technology. This new breed of chromatographic column allows you to more easily achieve peak separation and faster analysis times without expensive UHPLC instrumentation. Every LC lab has a cache of C18s, but every C18 is not created equal. Because t…

Force LC columns are available with Restek's most popular and highly selective Biphenyl and FluoroPhenyl phases, as well as a general-purpose C18.

Force LC columns are available with Restek's most popular and highly selective Biphenyl and FluoroPhenyl phases, as well as a general-purpose C18.

The culmination of 20+ years in LC, Force performance LC columns are long-lasting and reproducible, even under the stress of UHPLC. Premium quality is backed by the strength of our 100% Pure Satisfaction guarantee. And perhaps most important, Force columns are fully scalable between 3 or 5 μm HPLC and 1.8 μm UHPLC, so you can easily transfer and optimize methods without extensive calculations.   Force FluoroPhenyl LC…

Restek chemists became the first to combine the speed of superficially porous particles (also known as SPP or "core-shell" particles) with the resolution of highly selective USLC technology. This new breed of chromatographic column allows you to more easily achieve peak separation and faster analysis times with existing HPLC and UHPLC instrumentation.  Stationary Phase Category: Proprietary Ligand Type: Proprietary Partic…

The Ultra line represents Restek’s broadest selection of stationary phases on a single silica support. Made of high-purity, type-B silica that minimizes activity and creates high-density bonding, these columns are designed for selective and reliable HPLC applications.