GTxResolve SEC Columns

With size exclusion chromatography (SEC), analysts can quickly assess the aggregate content, integrity, heterogeneity, and purity of gene therapy drug substances. Waters GTxResolve SEC Columns incorporate breakthrough chemistry technologies for the fast analysis of large biological analytes and a number of first-of-their-kind multi-attribute quantitation assays.

Achieve new benchmarks in quality with high resolution, low adsorption, and robust GTxResolve SEC Columns for lipid nanoparticles (LNPs), nucleic acids, and viral vector analyses that:

• Accelerate aggregate and size variant analysis with high resolution that enables detection of low-level impurities
• Deliver reproducible data necessary for platform methods
• Improve cost savings with columns that maintain a long shelf life
• Achieve low secondary interaction enabling low MALS noise
• Provide low adsorption hardware necessary with biologics to enhance recovery