Biotage® Oligo SPE
The Biotage® Oligo SPE solid-phase extraction solution for bioanalysis of therapeutic oligonucleotides. Developed for efficient extraction of oligonucleotide-based therapeutics from biological samples, including plasma, serum, urine and tissue homogenates.
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Biotage® Oligo SPE enables accurate quantification of therapeutic oligonucleotides - even at low levels - by removing matrix interferences for cleaner, high-sensitivity LC-MS/MS results. Designed for high-throughput labs, it integrates seamlessly with automation and uses expert-developed protocols to minimize degradation and maximize recovery.
Solid-phase extraction solution for bioanalysis of therapeutic oligonucleotides
Explore the Biotage® Oligo SPE, a solid-phase extraction (SPE) solution specifically developed for efficient extraction of oligonucleotide-based therapeutics from biological samples, including plasma, serum, urine and tissue homogenates. Discover how by using mixed-mode weak anion exchange (WAX) chemistry, Biotage® Oligo SPE effectively removes interfering proteins, salts, sugars, lipids and DNA fragments. Its tailored sorbent design delivers clean extracts and consistently high recoveries across a variety of oligonucleotide structures and chemistries.
