Separations Products & Reviews

The ACQUITY UPLC® M-Class System with HDX Technology leverages UPLC® separations and high-resolution MS to answer important questions about changes in protein conformation including: Drug candidate binding to a protein Biopharmaceutical product development Protein-protein interactions Intellectual Property The unprecedented system-level design integrates all the steps necessary to accurately, reproducibly, and most o…

Ostro™ 96-well plate provides a novel solution for the cleanup of phospholipids in plasma and serum. Requiring minimal to no method development and using a simple protocol, this technology can be quickly implemented in order to optimize your laboratory's workflow. Removes significantly more phospholipids for cleaner extracts Improves reproducibility for more consistent, robust methods Increases throughput with easy-to-…

The Investigator SFC, an analytical to semi-preparative supercritical fluid chromatography system, combines the power of analytical SFC with the unique ability to isolate and collect less than 1 gram of specific compounds.It includes higher flow rates (up to 15 mL/min), a larger and more flexible oven that accommodates up to 10 analytical columns or 6 preparative columns. With the Alias Autosampler, the Investigator SFC delive…

Neutral alumina columns are useful when samples are acid sensitive and prone to degradation on normal phase silica gel. Acid and basic alumina columns are useful when purification of a compound with those properties is considered. This avoids the solvent swapping and additional extraction, washing, and concentration involved in recovering target compounds from collected fractions containing a mobile phase modifier such as tri…

The one-rack Foxy R1 fraction collector can be adapted to a broad spectrum of applications. The units can distribute fractions into 96 well microplates, standard tube sizes, and bottles. For essentially unlimited volumes, funnel racks can direct fluids to any collection vessel or downstream process. 

The two-rack Foxy R2 fraction collector can be adapted to a broad spectrum of applications. The units can distribute fractions into 96 well microplates, standard tube sizes, and bottles. For essentially unlimited volumes, funnel racks can direct fluids to any collection vessel or downstream process. 

High performance normal- or reversed-phase purification of compounds with basic properties.

RediSep Rf Gold C8 reversed-phase columns are packed with 20–40 µm spherical bonded silica, providing improved separation. Achieve near prep-HPLC results with greater sample recovery to easily purify up to gram-scale on your Flash system. Increased pore size optimized for purification of larger molecules like peptides and proteins.

Enhance analyte sensitivity up to 10 times and reduce interference  

One autosampler for both oils and coolants  

One autosampler for both oils and coolants  

Volumetric Sample Praparation Station

Gravimetric Sample Preparation Station

The CombiFlash NextGen 300 is configurable to your needs. Like the 300+, safety features including active vapor, solvent level and waste-level sensing are standard. The system is designed for liquid injections, operating at up to 300 psi (20 bar).

The CombiFlash NextGen 100 offers flow rates up to 100 mL/min and operating pressures up to 150 psi (10 bar). This is an economical, basic system designed to perform both normal and reverse phase purifications.

TSKgel Protein C4 is a reversed phase HPLC column for the separation of intact proteins.

TSKgel mAb SW SEC Columns – Setting new Benchmarks for Antibody Analysis.

TOYOPEARL MX-Trp-650M is a high capacity mixed-mode resin used for the purification of monoclonal antibodies and other proteins.

TSKgel UP-SW Series offers highest resolution based on established SEC technology.

TOYOPEARL AF-rProtein L affinity resin for the capture of mAbs and mAb fragments 

TOYOPEARL Sulfate-650F offers a high binding capacity for IgG across a range of pH values and conductivities

SkillPak 1 (0.7 cm ID x 2.5 cm L, CV 1 mL) and 5 (0.8 cm ID x 10 cm L, CV 5 mL) pre-packed columns offer a reproducible and efficient solution for screening and initial developing of purification methods for biomolecules. SkillPak 50 and 200 mL pre-packed columns are the best solution for seamless scale up of methods developed on SkillPak 1 and 5. 

The TSKgel UP-SW3000-LS UHPLC column analyses biotherapeutics by size exclusion chromatography and is designed for the combination with MALS and MS.

TOYOPEARL HW-50S resin is a hydroxylated methacrylic polymer for size exclusion chromatography.

Octave BIO intensifies your downstream processing productivity