Drug discovery > Pre-Clinical Development Products & Reviews

The CellTiter-Glo® 2.0 Assay provides a homogeneous method for determining the number of viable cells in culture by measuring the amount of ATP present, which indicates the presence of metabolically active cells. The CellTiter-Glo® 2.0 Assay is based on the original CellTiter-Glo® Assay chemistry but with improved storage convenience for easy implementation. The CellTiter-Glo® 2.0 Assay is provided as a single, ready-to-use re…

The Lactate-Glo™ Assay is a bioluminescent assay for rapid, selective and sensitive detection of L-lactate in biological samples. Lactate is produced by glycolysis, a major metabolic pathway responsible for glucose homeostasis and energy production (1,2). Once considered merely a byproduct of glycolysis, lactate is now considered an important regulatory molecule of intermediate metabolism involved in cancer development, diabet…

A Fluorometric Method for Estimating the Number of Nonviable Cells Present in Multiwell Plates

A Simple, Non-Radioactive Assay to Measure Glucose Uptake Inside Cells

Digitonin can be used in cell viability and cytotoxicity assays. It is a detergent solution useful for permeabilizing cells and for creating a cytotoxicity chemistry positive control. Supplied at 20mg/ml in DMSO

The Caspase-Glo ® 3/7 Assay System is  a highly sensitive caspase activity assay for use in plate-reader assays.

The CellTiter 96® AQueous One Solution Cell Proliferation Assay is a colorimetric method for determining the number of viable cells in proliferation, cytotoxicity or chemosensitivity assays. The CellTiter 96® AQueous One Solution Reagent contains a tetrazolium compound [3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium, inner salt; MTS(a)] and an electron coupling reagent (phenazine ethos…

The GSH-Glo™ Glutathione Assay is a luminescence-based assay for the detection and quantification of glutathione (GSH). The assay is based on the conversion of a luciferin derivative into luciferin in the presence of glutathione, catalyzed by glutathione S-transferase (GST). The signal generated in a coupled reaction with firefly luciferase is proportional to the amount of glutathione present in the sample. Luminescence is gen…

The Waters® MV-10 ASFE™ System is the first supercritical fluid extraction (SFE) system offering accelerated, multi-vessel sample extraction, resulting in a faster, greener, more selective alternative for analyte extractions from a wide variety of sample matrices. Whether your workflow requires enriching target analytes for analytical purposes, stripping unwanted material from a product, or collecting valuable essential oils f…

Empower™ 3 Method Validation Manager (MVM), an option for Empower 3 Chromatography Software, allows you to perform chromatographic method validation, from protocol planning through final reporting, in one application.With Empower 3 MVM you can automatically: Manage method validation workflow in one comprehensive, automated application Clearly display the status of ongoing validation studies – enabling you to see at what…

Live-cell analysis system

Fast, accurate, and automated brightfield and fluorescent cell counting

Lux3 BR is a small brightfield live-cell imager, equipped with a high-quality 6.4 MP CMOS camera. It is designed to work inside a standard cell culture incubator without disturbing temperature, airflow, and optimum culture conditions. Detailed brightfield images can be captured using the new device. In both x- and y-direction, 2072 pixels combined with 1.45 mm field of view provide a resolution of 0.7 µm/pixel. 

High-throughput live-cell analysis system

The Specac Mini-Pellet Press is an entry-level laboratory hydraulic press for the preparation of high-quality 7mm KBr pellets for transmission FTIR analysis. With a rugged and durable design, this press is intended for regular laboratory use with maintenance-free operation. Specac’s Mini-Pellet Press is designed to be used on a laboratory benchtop, but is small in size and light enough in weight to allow it to be moved to d…

Macro to Micro Fluorescent In Vivo Imaging - Now researchers can take detection of fluorescent markers in small animals to a new level with the UVP iBox Explorer 2 Imaging Microscope!   

The UVP ChemStudio series imagers are used for high sensitivity imaging of Western blots, fluorescent Westerns, immunoblots, protein blots, DNA gels, protein gels, blue light gels, colony plates and a wide range of stains and dyes.   

The UVP iBox Scientia Small Animal Imaging System is designed to automate your in vivo small animal imaging research with one-touch, pre-set or user-defined PC controls for accurate, repeatable imaging.   

Absorbance 96 Automate is the truly on-deck plate reader in the world. With its small footprint, lightweight, and z-axis serviceability, Absorbance 96 Automate is designed for modular integration and can be serviced by a wide range of robotic systems, from traditional decks to state-of-the-art modular systems. 

Research and clinical upright microscopes that support research in the fields of biological science and medicine, with excellent optical performance and high system expandability that can be equipped with motorized accessories.

Compact and economic flow cytometer

Preparing cell suspensions without strain

Reagent kit for nuclei extraction and DNA staining of nuclear DNA from plant tissues to determine absolute and relative genome size and ploidy level. CyStain PI OxProtect is especially formulated to prevent oxidation and degradation processes triggered by endogenous plant tissue oxidants. The reagent has been created specifically for selected configurations of the Sysmex CyFlow Ploidy Analyser and CyFlow Space flow cytometers.…

Reagent kit for nuclei extraction and DNA staining of nuclear DNA from plant tissues to determine absolute and relative genome size and ploidy level. The reagent has been created specifically for selected configurations of the Sysmex CyFlow Ploidy Analyser and CyFlow Space flow cytometers.

ADAM™ CellT Plus is an advanced automated cell counter featuring bright field and two fluorescence channels (AO/DAPI), ensuring highly accurate cell counting. It offers a comprehensive solution tailored to meet the requirements of 21 CFR Part 11 within cGMP production environments.