Drug discovery > Basic Research Products & Reviews

The easiest of HPLC systems to operate, without compromising build quality.

Q5® Site-Directed Mutagenesis Kit enables rapid, site-specific mutagenesis of double-stranded plasmid DNA in less than 2 hours. The kit utilizes the robust Q5 Hot Start High-Fidelity DNA Polymerase along with custom mutagenic primers to create insertions, deletions and substitutions in a wide variety of plasmids. After PCR, the amplified material is added directly to a unique Kinase-Ligase-DpnI (KLD) enzyme mix for rapid, roo…

An innovative, polymeric system for efficient delivery of plasmid DNA and siRNA/miRNA. Experience the transfection breakthrough. Achieve superior transfections with an innovative polymeric system that efficiently delivers both DNA and RNA out of the endosome and into the cytoplasm overcoming a critical barrier to nucleic acid delivery.Head-to-head comparisons against the Lipofectamine® 2000 illustrate superior or equal lucife…

The Thermo Scientific* BRAHMS* PCT Immunoassays are immunofluorescent assays used to determine the concentration of PCT (procalcitonin) in human serum and plasma. The Thermo Scientific* BRAHMS* PCT Immunoassays are intended for use in conjunction with other laboratory findings and clinical assessments to aid in the risk assessment of critically ill patients on their first day of ICU admission for progression to severe sepsis…

The NEBNext® DNA Library Prep Master Mix Set for Illumina® contains enzymes and buffers in convenient master mix formulations that are ideally suited for sample preparation for next-generation sequencing, and for preparation of expression libraries. NEBNext® reagents are a series of highly pure reagents that facilitate sample preparation of DNA or RNA for downstream applications such as next generation sequencing and expressi…

he NEBNext® Ultra™ DNA Library Prep Kit for Illumina contains enzymes and buffers that are ideal to convert a small amount of DNA input into indexed libraries for next-generation sequencing on the Illumina platform (Illumina, Inc). The workflow of NEBNext Ultra DNA Library Prep Kit for Illumina is very user-friendly and fast with minimal hands-on time.NEBNext® reagents are a series of highly pure reagents that facilitate samp…

NEBNext® dsDNA Fragmentase® generates dsDNA breaks in a time-dependent manner to yield 100–800 bp DNA fragments depending on reaction time. NEBNext dsDNA Fragmentase contains two enzymes, one randomly generates nicks on dsDNA and the other recognizes the nicked site and cuts the opposite DNA strand across from the nick, producing dsDNA breaks. The resulting DNA fragments contain short overhangs, 5´-phosphates, and 3´-hydroxyl…

The NEBNext® mRNA Library Prep Master Mix Set for Illumina® contains enzymes and buffers that are ideally suited for sample preparation for next-generation sequencing, and for preparation of expression libraries. NEBNext® reagents are a series of highly pure reagents that facilitate sample preparation of DNA or RNA for downstream applications such as next generation sequencing and expression library construction. The reagents…

BioDrop μLITE is the only choice for micro-volume measurement when you need speed without sacrificing accuracy or precision. With no moving parts, the unique in-built sample port offers unrivalled performance delivering a dsDNA detection limit of 1ng/μL. Because the pathlength doesn’t change, the instrument provides excellent measurement reproducibility. Measurements made with the BioDrop μLITE are also highly accurate becaus…

BioDrop DUO UV/Vis spectrophotometer has two measurement modes: a unique in-built sample port unrivalled dsDNA detection limit of 1ng/μl PLUS a cuvette holder for the revolutionary BioDrop CUVETTE 125, ideal for highly concentrated samples. BioDrop DUO is quick and easy to use. It has a large capacitive colour touch screen with on-board software for data acquisition and analysis. Pre-programmed methods for DNA, RNA, oligos and…

A high efficiency, low toxicity, DNA transfection reagent optimized for 293 cellsTransIT®-293 Transfection Reagent is specifically optimized to provide exceptional transfection efficiency of plasmid DNA in HEK 293 and cell types of associated lineage. TransIT-293 provides all the attributes of the trusted TransIT series of transfection reagents: high transfection efficiency, low toxicity, serum compatibility, simplicity of use…

TransIT-TKO® is a broad spectrum siRNA transfection reagent that enables high efficiency siRNA delivery and knockdown of target gene expression in many cell types including primary cells.

High binding surface is capable of binding medium (>10kD) and large biomolecules that possess ionic groups and/or hydrophobic regions Binding capacity is approximately 400 to 500ng IgG/cm2 Ideal for immunoassays Without lids, lids supplied separately Total volume is 360 µL; recommended working volume of 75 to 200 µL Conforms to standard microplate footprint and dimensions

Round bottom wells with 330 µL total volume Recommended working volumes of 75 to 200 µL Nonreversable lids with condensation rings to reduce contamination Treated for optimal cell attachment Sterilized by gamma radiation and certified nonpyrogenic Individual alphanumeric codes for well identification Individually wrapped

Obtain high quality results with this thermostable probe-based qPCR master mix

Incorporating Shimadzu’s proprietary ultrafast technologies (UF Technologies), the new triple quadrupole LCMS-8050 dramatically improves analytical throughput with the ultimate in high-speed performance.   In addition, the newly designed ion source and collision cell, Heated-ESI and UFsweeper® III collision cell technology, ensure the highest levels of sensitivity and quantitative performance. Combine with Shimadzu’s wo…

High performance, versatility and ease-of-use in a compact design for efficient mass spectrometry analysis.

The Thermo Scientific™ HyPerforma S.U.B. TK 250L system combines the experience of hundreds of single-use stirred-tank bioreactors used in the industry today with a state-of-the-art controller system for a turnkey bioprocessing solution.This out-of-the-box solution dramatically shortens implementation time and reduces upfront cost while providing all the advantages of our open-architecture single-use bioreactors (S.U.B.). HyP…

The MiSeqDx instrument is the first and only FDA-cleared in vitro diagnostic (IVD) next-generation sequencing (NGS) system. Designed specifically for the clinical laboratory environment, the MiSeqDx instrument offers a small, approximately 4 square feet (0.37 square meters) footprint, an easy-to-follow workflow, and data output tailored to the needs of clinical labs. In addition, the integrated software enables sample trackin…

Merck Millipore’s Singlepath® Lateral Flow Tests are immunoassays for detecting pathogens with the ultimate convenience. Covering the major pathogens, the tests act as mini-laboratories in the “pregnancy test” format and always include a built-in control reaction. Another major advantage is that they deliver definite results as little as 20 minutes after sample enrichment.Merck Millipore Lateral Flow Tests offer all the benef…

Petrifilm™ Rapid Yeast and Mold Count Plates - Rapid, labor-saving technology for product and environmental testing.Yeasts and molds can grow in a wide range of conditions in your raw materials, finished product and production environment, making them difficult to control. Complicating matters is the five-day incubation period required by traditional agar methods. 3M™ Petrifilm™ Rapid Yeast and Mold Count Plates are a faster,…

For high performance imaging, the new generation of G:BOX Chemi gel doc systems provide the user with an extended range of applications covering fluorescence and chemiluminescence. All these systems now utilise Syngene’s groundbreaking GeneSys automatic control software. Driven from a database containing hundreds of capture protocols, full manual control is available should you wish to use it. The G:BOX Chemi series feature…

Shimadzu’s BioSpec-nano spectrophotometer is a low-maintenance micro-volume spectrophotometer designed for the modern life science laboratory. Its easy-to-use design and superior detection limits, up to 10 times better compared to the competition, make it the perfect instrument for quantitation of DNA, RNA, protein analysis, and photometric measurements. The BioSpec-nano features: Ultra-small sample volumes (1µL to…

The most popular amine-reactive biotinylation reagent for antibody labeling Thermo Scientific™ EZ-Link™ Sulfo-NHS-LC-Biotin and Labeling Kits Features: Water-soluble analog of NHS-LC-Biotin Reacts with primary amines at pH 7-9 in non-amine-containing buffers such as borate, carbonate or phosphate buffers Negative charge of -SO3 group keeps biotinylation localized at the cell surface Creates an amide bond Applicatio…

The PCT Pre-Crystallization Test is used to determine the appropriate protein concentration for crystallization screening. Sample concentration is a significant crystallization variable. Samples too concentrated can result in amorphous precipitate, while samples too dilute can result in clear drops. Precipitate and clear drops are typical crystallization screen results for reagent conditions which do not promote crystallizati…