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TSKgel® UP-SW3000-LS SEC column for MALS and MS by Tosoh Bioscience

Manufacturer Tosoh Bioscience
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The TSKgel UP-SW3000-LS UHPLC column analyses biotherapeutics by size exclusion chromatography and is designed for the combination with MALS and MS.


TSKgel® UP-SW3000-LS SEC column for MALS and MS by Tosoh Bioscience product image
TSKgel® UP-SW3000-LS SEC column for MALS and MS
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TSKgel UP-SW3000-LS UHPLC columns analyze monoclonal antibodies and other biotherapeutics by size exclusion chromatography with high resolution. The key feature of this column is its noise suppression in downstream detection methods such as light scattering and MS. That not only facilitates and accelerates their addition but also improves analysis performance.

Features:

  • 2 µm particles for fast and high resolution separations
  • 25 nm pore size for proteins of 10-5000 kDa, such as mAbs
  • Reduced noise in light scattering applications
  • Short equilibration times for MALS and MS detection
  • High and stable ionization efficiency by ESI

Column specifications:

  • Diol-bonded silica with particle size 2 µm
  • Pore size: 25 nm
  • Calibration range (globular proteins): 10-500 kDa
  • Hardware: stainless steel
  • Inner diameter: 4.6 mm
  • Length: 15 cm or 30 cm
  • Application: MALS and MS analysis of biotherapeutics