TSKgel mAb SW Gel Filtration Columns for Antibody Analysis by Tosoh Bioscience

TSKgel mAb SW SEC Columns – Setting new Benchmarks for Antibody Analysis.

TSKgel SW size exclusion columns – the industry’s workhorse for aggregate analysis - continue to set standards for the UHPLC separation of antibody fragments, monomers, and aggregates. TSKgel SW mAb  columns are tailored to different aspects of antibody analysis: 

• TSKgel SuperSWmAb HTP supports high throughput antibody analysis through a shorter column length and smaller diameter. 
• TSKgel SuperSWmAb HR, designed for high resolution monoclonal analysis, is packed in columns featuring the conventional dimensions for HPLC gel filtration columns. This allows for superior resolution between fragments, monomers, and aggregates. 
• TSKgel UltraSW Aggregate covers the range of higher molecular weights and provides a very good separation of antibody dimers and higher aggregates. It is based on 3µm silica particles with slightly larger pore size than the SuperSW mAb columns. 

TSKgel SuperSW and UltraSW particles are based on highly porous, ultra-pure silica particles, the surface of which has been shielded from interacting with proteins by applying a proprietary surface chemistry. This ensures highest recoveries and accurate quantitation. TSKgel SW columns stand out from other silica-based high performance size exclusion columns by virtue of their large pore volumes. The validated manufacturing and packing process ensures a reliable batch-to-batch reproducibility.