Member since: 2015
Organization: TATA Advanced Systems Limited
The buffer solution accuracy is very precious.
Application Area: Analyze water samples and acid samples
"The manufacturer's material gives tremendous performance during analysis."
Traditionally cation-exchange chromatography using salt gradients has been successfully used to characterize MAb charge variants. However, additional effort is often required to tailor the salt gradient method for individual charge variants. Thermo Scientific™ pH buffer solutions and kits can be used to generate highly reproducible, linear pH gradients using cation-exchange chromatography.
This generic, LC-based platform approach saves time in method development and facilitates method transfer to QA/QC for a wide range of MAb charge variants. Unlike traditional salt gradients, it is possible to predict the pI and the expected retention of the charge variants and use a narrow pH range to get a higher resolution separation.
pH Gradient Buffer Solutions Features: