Thermo Scientific™ NanoDrop™ One/OneC Microvolume UV-Vis Spectrophotometer with Wi-Fi by Thermo Fisher Scientific

"It is a novel instrument for micro analysis of samples at molecular level. Really it is very effective, but as in this case very latest technology is used( being digital), so the scientific community is still far away and most of them are unaware about it. So popularization of this tool is very necessary. I have used only once and found it very effective as it presents accurate data in digital mode."

"This product is excellent and does not require sophisticated expertise"

"The NanoDrop One is very easy to use, with minimal sample loss. Be sure your sample is diluted to within the linear range of the instrument."

"This is easy to use and gives excellent results."

"Very easy and precise machine for the quantification of nucleic acid like DNA or RNA. I use this almost every day for the quantification of extracted samples and have found it very effective. Happy to work with this."

"Good results, precise and accurate."

"I have always been a NanoDrop fan but I love some of the new features in the NanoDrop One. NanoDrop has always demonstrated accurate results with good ease of use which is a huge benefit when training new people in the lab! I love that it now identifies potential contaminants in your samples. This is a huge bonus for training new people. Ours is a common use piece of equipment and it holds up well to multiple labs using it."

"The accuracy of the results is poor. Compared with a different brand, it takes a longer time to analyze. Initialization takes more than a few minutes. Cleaning of the pedestals is frequently required. After one year of usage, I regret buying it."

"The machine is easy and highly self-explanatory in nature. High probability of getting accurate result as the digital interpretation of the results is very easy to understand. "

"The instrument is quite fast and reliable. It gives robust values and it is a perfect device for a quick measurement with a very low liquid quantity."

"We switched from our classical UV spectrophotometer with cuvette to a Nanodrop and everybody in the lab is delighted. Easy to use, clean, has very good accuracy and reproductibility. Our nanodrop allows us to have immediate dosage of our proteins. The possibility to define custom methods, to export the raw data simply on our netswork is a plus."

"The best one yet. It is of good quality, easy to use and it gives accurate results. I always recommend it."

"Easy to use, easy to maintain. The menus are easy to follow without much problems."

"Extremely easy to use spectrophotometer. Results are reproducible and the contamination warnings zero in on mistakes that were made during extraction (phenol, ethanol carry over). Easy to care for and great value for money, especially if you need the added capability to use cuvettes."

"Highly reproducible results and straightforward. Anyone can use it with limited training."

"The nanodrop requires no major amount of upkeep. It is easy to train someone to use. Love the touch screen."

"It works great but its not as intuitive to use as some other devices. it was a steeper learning curve for my team and the location of buttons were not intuitive. It gets the job done though. Ours is shared amongst many labs and is used for diverse needs."

"This new instrument replaced the old one that we had from 10 years. This instrument is reliable, faster and easier to use."

"Highly recommend the NanoDrop One UV-Vis Spectrophotometer for ease of use, small footprint and stand alone use with no computer required. Gives reliable results and easy to take care of too."

"The Nanodrop One by ThermoFisher has an easy to use software interface with ample digital support resources and regularly held webinars. The Auto-Measure design was developed with the end user in mind."

"We have purchased several NanoDrop Ones for use in undergraduate practicals. Students and staff really enjoy using the machine, due to the rapid, reproducible analysis of results and modern aesthetic, including a touchscreen. The machine is also compact and portable, removing the need for a PC and making it ideal for undergraduate practicals. It includes a number of useful features for teaching in molecular biology."

"Great piece of kit, even easier to get reliable results quickly. Love the built in guidance and trouble shooting, small footprint and simplified so it's equally effective for all users."

"The NanoDrop OneC is a very versatile spectrophotometer for the daily lab routine. Offering both the pedestal and a cuvette option, a wide variaty of samples can be analyzed. The instrument offers a touchscreen display and can directly be connected via Wi-Fi. It has a small footprint and can easily be moved around in the lab."

"Great product, we use it every day, vital product to measure DNA."

"The Nano Drop One is very easy to use; however it has some automatic steps where we would prefer that the machine waited for the user to initiate the next step. Our first instrument was bad-out-of-the-box so there was some delay while it was returned etc. Before we had a working replacement. Fisher staff were great in handling the replacement process."

"Very easy to use machine that initially had a few software bugs but is now working fine"

"This instrument is incredibly valuable and saves time and lessens antibody waste."

"This instrument has been extremely efficient and effective. There are many options to choose from that allow for easy of use. I have confidence that if I need it for applications other than what I am currently using it for, I will be able to do so with the same ease. Additionally, I had one problem with the software but that issue was easily resolved with the support team."

"We have used the NanoDrop One for about one and half years and we are very happy with it. Using it is very easy and you almost don't need any guidance. The UI is also very straightforward and self-explanatory. In addition the services is also very prompt"

"The main advantage of the NanoDrop is that it requires a very small (2-3uL) of sample, while still maintaining a broad dynamic range and sensitivity relative to a conventional spectrophotometer. You can measure one sample at a time or purchase the 96-well version that measures a plate at at a time. The only weakness of the system is the software is some what limited; for instance, you can not obtain concentration of protein if the extinction coefficient is known. Of course, you can calculate it yourself from the the A260. Other than some minor inconveniences, this is a workhorse in our department."

"Very effective, convenient, fast, easy to use and save samples."

"We use the Nanodrop One in our undergraduate biology lab courses. Each semester they are used by ask many as 300 students. We believe that the accuracy and consistency of the readings is more than adequate for use in a student lab. The students find the Nanodrop easy to use and do not make many mistakes while using it. Since the student preps are sometimes "dirty", the Nanodrop is helpful in letting them know that their sample may be contaminated and what the contaminates may be."

"For standard A280 measurements, the product works fine. We use on daily basis to quantify membrane proteins -- Measurements are replicable, but tend to be only qualitative measures (as are most other low volume spectrophotometric measurements). However there are major issues with utilization of the cuvette measurement; namely an inability to blank with anything other than water. Doing Bradford or A600 measures generates an error with the blank. Furthermore, we purchased with the cuvette so that media and dye would not be used on the nanodrop pedestal portion of the machine. This being said the nanodrop is still the best commercial option for quantifying membrane proteins but i would counsel against purchasing with the cuvette."

"We have been using a NanoDrop since the beginning (I don't remember the beginning - could be BC...) and with the all new One C, NanoDrop moved it to the next level. It is so easy to use, takes just seconds to run your samples after you turn your device on... I don't think that I need to talk about the reproducibility and sensitivity of any Nanodrop, everyone knows. But this one has a wonderful user interface. Together with the PC viewer, the graphs are ready to use on your publications. I still could not manage to set up the wifi because we are working in a strictly safe governmental facility with high internet safety, but I will find a way to do this too. I am sure that will also be fancy :) I definitely suggest this little cute guy to anyone who is working with DNA, nucleic acids, bases etc... wherever you need a spectrometric analysis... You will see that you got more than every penny you spent..."

"It is easy to use, and understand, straight forwards. user friendly and give us a high quality quant for DNA."

"This product is awesome, we use it on a daily basis. Even novices in my lab find the the instrument very easy to use as it walks you through the entire quantification process. In addition, I love the fact that it has a really small footprint in my lab. I also have a Nandrop 2000C which, while works well, has now fallen by the wayside due to the sheer ease of use with the NanoDrop ONE C. I honestly couldn't imagine my lab without this little gem."

"Very user friendly. Has more functionality then we need but is nice to have for future."

"I love our NanoDrop! It is nice to only have one instrument taking up space that can do so many things. I use it almost every day to either quantify DNA or RNA and check ODs of cells. I have also found the Bradford settings really helpful and straightforward for quantifying protein when I have occasionally needed to do that and I was even able to calculate enzyme activity using the enzymology program it has. My only complaint about the instrument is that occasionally it "freezes"; however, this tends to be resolved with the faithful "turn it off and back on again" solution."

"The nanodrop is one of the most used instruments in my lab. It is almost used everyday sometimes several times a day. We use it for measuring DNA, RNA and Protein at absorbance 280 nm. I liked the previous nanodrop better that had a computer attached to it and it was more robust. This one with the tablet crashes a lot and we have restart it often."

"For my applications everything is great especially combination of nanodrop and standard cuvette capabilities. As an idea for further development I'd suggest light guides for Abs measurements in biological objects with non-standard shapes like for example jellyfish"

"This nanodrop is very effective and reliable. I had no issues with it."

"We love the Nanodrop One. We love that it is stand alone - no separate computer needed. We love that it initializes and then we can just blank it. We do need to print from it sometimes, so we would like it if it could be linked to a printer. Currently - we work around that by using a memory stick to transfer the data to a computer."

"The nanodrop one is easy to use and replicates prove it’s accuracy and reproducibility. We have encountered some hiccups in the software where it will freeze, but a restart solves the issue. Simply download the results to a thumb drive and view them on any computer with the software."

"We've greatly enjoyed the new NanodropOne, which was a huge upgrade from our 1000. We decided to take advantage of a trade-in offer because our old device was giving errors and was unable to be calibrated. Since day 1 with this new equipment, everything has been easier. All the steps have been streamlined and it is beyond user-friendly. While we had both devices, I ran a few samples on both. While the 1000 had trouble giving consistent reads, the One can accurately measure the same sample with ease. If I had to pick one "fault" with this device, it's that I fear the touch screen could have issues down the road. That is the biggest change, as the old device was attached to a computer. We've had no issues at this point, but in my experience, the screens are usually the first to go. That being said, I don't expect any issues in the immediate future and I feel those issues are to be expected overtime. Overall, we are thrilled with this new equipment and would purchase again."

"We've been very happy with our NanoDrop One. It's been a great friend to us in the lab! What we've been most impressed with, however is how responsive Thermofisher has been in all of our troubleshooting and technical support needs. Even minor issues with the machine were addressed promptly over the phone and email with excellent follow up. When we needed to send the machine out for repair, we were provided a loaner instrument and all of the shipping supplies promptly which enabled us to continue experiments without any disruption to workflow. We always had a direct line to someone for any follow up concerns or needs. Highly recommend!"

"We've been using the Nandrop since it came on the market and the Nanodrop One has offered us a smaller footprint and an easy to use format."

"Overall very happy with the NanoDrop One. We had a few hiccups with software crashing at first but customer service quickly addressed our issue and there is not been a problem since. The small footprint is very nice and the instrument performs exactly as we need. Being able to easily transfer data via a thumb drive is a nice feature."

"This is a truly plug and play instrument. No additional parts or equipment is required. Easy to use, accurate enough for our applications. A presence of the Cuvette option makes it an ideal choice ."