Strata® Solid Phase Extraction

Download this application note to find a method where an LCS sample was extracted with Strata PFAS and analyzed on an LCMS/MS system using a Gemini® 3 µm C18 HPLC column under the conditions described in a previously published GenX Application Note.

This application note demonstrates the preparation and extraction of corticosteroids from urine samples using Phenomenex Solid Phase Extraction (SPE) and Kinetex Core-Shell LC Columns.

This application note details some common problems caused during environmental sample analysis and provides solutions through a wide variety of sample preparation kits.

The world is changing and we need to widen our Environmental Scope. Although analytical techniques and established regulated methods are not easily changed; more complex targets, larger lists, and a variety of sample matrices create a daily challenge for environmental chemists. By using the latest technologies and techniques in HPLC/ UHPLC and Sample Preparation, laboratories and chemists are able to develop better approaches to make their work Faster, Cheaper and Easier. Phenomenex is committed to supporting the industry through a comprehensive product portfolio of Sample Preparation, HPLC/UHPLC, and LC-MS, columns and accessories, along with application and method development services to meet industry needs.

This application note discusses sample preparation techniques for a variety of clinical samples for simplified liquid extractions (SLE) and solid phase extraction (SPE).

This clinical notebook contains a variety of 36 application notes, covering topics in endocrinology and biomarker research, therapeutic drug monitoring, toxicology and sample preparation.

Nicotine, its metabolite cotinine, and anabasine, a tobacco alkaloid, are often used to detect tobacco exposure. For tests like this, oral fluid collection has emerged as an alternative to other biological matrices. The additives and preservative buffer (critical for preservation of the chemical integrity of the oral fluid sample) present in the collection devices, must be removed for the proper upkeep of the mass spec detector. This technical note presents a solid phase extraction (SPE) method for simultaneous detection and quantitation of nicotine, cotinine, and anabasine from oral fluid.

Use of oral fluid as a drug testing matrix has steadily gained popularity due to its easy and non-intrusive sample collection procedure. The oral fluid collection device provides a buffer solution that contains a number of antibacterial agents and surfactants which acts to prevent bacterial growth and increase the analytes stability during the sample transit to testing laboratories. Presented is a fast sample preparation procedure to reduce detrimental effect of excipients present in the buffer solution of the device.

This application note gives a complete and comprehensive guide to developing your SPE method, including choosing a sorbent, pre-treatment of the sample, general starting methods for Strata-X and for Strata, industry applications and ordering information.

Pesticide contamination is not limited to produce items. Animals used for food consumption are also exposed to contaminants at levels that can pose harm to the human population. Presented in this application note is a method developed using SPE and GC/electron capture detector (ECD), for pesticides analysis from poultry fat. It shows how this method improves upon the traditional procedure, resulting in a 75% reduction in laboratory space, reduction of hazardous waste, and a 50% reduction in labor consumption, leading to greater laboratory productivity.

This solid phase extraction (SPE) demonstration using colors shows the best techniques to use when working with SPE and how to best approach SPE.

Watch this on-demand webinar to discover how you can reduce sample handling and sample preparation time for non-drinking water PFAS analysis

Richard Thomas, CSO, Precision Diagnostics, discusses use of HPLC at leading drug detection laboratory