Phenomenex and Tecan to Co-Market Automated Sample Preparation Solutions

8 Sept 2015
Lois Manton-O'Byrne, PhD
Executive Editor

Phenomenex, Inc. and the Tecan Group today announced a collaboration to co-market automated solid phase extraction (SPE) sample preparation solutions. The two companies will jointly market Phenomenex Strata™ and Strata-X SPE sorbents adapted to Tecan’s Freedom EVO® series of robotics workstations.

The solution is especially geared to high-throughput customers in pharmaceutical research, clinical and food testing environments using mass spectrometry detection methods. As part of the global agreement, Tecan will provide the instruments and automation support, and Phenomenex will provide the extraction chemistries as well as application and method development through its PhenoLogixSM group.

Solid phase extraction is a widely used sample preparation technique by which compounds in mixtures are separated, prior to chromatographic analysis. Phenomenex Strata and Strata-X SPE sorbents remove unwanted contaminants, including phospholipids, and are offered in a number of unique selectivities to cover a diverse range of analytes. SPE can be a time-consuming manual process that is prone to human errors resulting in additional time and costs for laboratories to confirm or repeat tests. Execution of this process on Tecan automated platforms combined with optimized conditions from PhenoLogix will decrease implementation efforts in the lab, increase throughput while reducing human error and enable sample traceability for regulated environments.

“We created this agreement with our high-throughput customers in mind,” commented Michael McGinley, core products manager for Phenomenex. “We can now bring them complete, automated solutions, simplifying the previously daunting task of adapting a manual method to laboratory automation. The engineers at Tecan have an amazing insight on how to optimally automate liquid handling and the Freedom EVO is a proven platform with an established track record for reliability.”

“Phenomenex has a large customer base using their SPE products,” explained James O’Brien, Head of Clinical Diagnostics for Tecan. “By co-marketing our robotic workstations with their chemistries, we expect to expand our reach in these high-volume industries. The experts at Phenomenex and PhenoLogix have enhanced our knowledge of chromatography and enabled us to bring to market a product for mid- to high-throughput laboratories that increases the ROI of their high capital investment in mass spectrometry detection systems.”

Freedom EVO® NGS Workstation

Tecan

The Freedom EVO NGS workstation combines Tecan’s expertise in laboratory automation with sequencing-verified protocols to offer hassle-free NGS sample prep at the touch of a button. NGS is the fastest growing application in genomics, yet many sample preparation protocols can be labor intensive and time consuming. The Freedom EVO NGS workstation has been developed to offer robust and reliable automation of library preparation, quantification, qPCR set-up, normalization, pooling and capture. Offering user-friendly, walkaway automation at the touch of a button, it eliminates the need for extensive manual processing, helping to simplify day-to-day activities and ensure high quality results. Freedom EVO NGS workstation includes all the modules required for precise set-up of NGS sequencing libraries and, with one-touch method selection and step-by-step user instructions via Tecan’s intuitive TouchTools™ graphical interface, it reduces hands-on time and increases productivity – even for inexperienced users. The system’s key benefits include: Precise pipetting – from 1,000 µl down to 0.5 µl using eight pipetting channels and innovative air displacement pipetting technology Integrated temperature control – to keep reagents cool and provide optimal enzymatic conditions Efficient bead clean-up –  using a 96-position magnetic plate separator (Alpaqua 96S Super Magnet Plate) Walkaway processing – with on-board consumables storage for long unattended runs Straightforward operation – with step-by-step set-up instructions To further streamline processing, Tecan has worked with leading industry partners to supply ready-to-run protocols for a number of popular NGS technologies. Protocols for Illumina’s TruSeq™ Nano DNA, TruSeq Stranded mRNA* and Nextera™ Rapid Capture Exome* chemistries have been developed in collaboration with Illumina and the High-Throughput Sequencing Facility, University of North Carolina at Chapel Hill, with thorough testing and sequencing data analysis to ensure high quality results. In addition, the system is supplied with protocols covering the Ion Torrent™ library preparation workflow for Ion AmpliSeq™ panels, developed and supported by Thermo Fisher Scientific. *Illumina-qualified protocol.

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