N-SIM S Super-Resolution Microscope System by Nikon Instruments

Manufacturer Nikon Instruments  |  Available Worldwide
The N-SIM S high-speed structured illumination super-resolution microscope achieves acquisition speeds of up to 15 fps. It enables fast biological processes to be captured at twice the spatial resolution of traditional diffraction limited light microscopes (up to 115 nm in XY). Combining the N-SIM S and a confocal microscope, such as the new A1R HD25, offers high flexibility, high content, high speed and super resolution to unravel biological details – high context and super resolution on one... Read more


N-SIM S Super-Resolution Microscope System by Nikon Instruments product image
N-SIM S Super-Resolution Microscope System
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The N-SIM S high-speed structured illumination super-resolution microscope achieves acquisition speeds of up to 15 fps. It enables fast biological processes to be captured at twice the spatial resolution of traditional diffraction limited light microscopes (up to 115 nm in XY).

Combining the N-SIM S and a confocal microscope, such as the new A1R HD25, offers high flexibility, high content, high speed and super resolution to unravel biological details – high context and super resolution on one platform. The A1 R HD25 offers resonant scanning and the largest field of view, enabling you to image the complete area of interest with fewer frames more rapidly. The combination offers the flexibility to use Galvano confocal imaging for high resolution and signal-to-noise ratio with the ability to switch effortlessly to N-SIM S to resolve subcellular details at super resolution using Nikon’s software interface – without disturbing the samples. A wide range of objectives is available, optionally with the auto correction collar, to optimise your experiments. Easily obtain up to 115 nm XY resolution and 269 nm Z resolution and record dynamic events in fine details in live cells with gentle illumination at up to 15 fps with N-SIM S.

Get more data, more information and higher context:

  • Set up automated confocal to SIM workflows using the powerful software feature JOBS
  • Screen for specific structures in the confocal images based on chosen criteria with General Analysis, and acquire SIM images of these structures seamlessly 

Save time and remove human subjectivity through automation