Monolith — the only way to get binding affinities in solution using very minimal sample
Directly measure the strength of molecular interactions in solution, without the need for immobilization. Characterize nearly all types of molecular interactions — even the most challenging ones. With ultra-low sample consumption and versatile capabilities, Monolith is the best solution for your binding affinity experiments.
Use Monolith as your trusted orthogonal tool to validate binding results or to get a Kd in challenging situations that SPR can’t handle. Monolith works great for countless molecules and buffers so you’re able to tackle the wide variety of projects that come your way.
Rely on Monolith’s versatile capabilities to execute immobilization-free experiments quickly and efficiently. Use Monolith to:
*Requires offline data handling, not supported by Monolith software
Monolith X with Spectral Shift and MST technologies
Monolith X is equipped with Spectral Shift and MST technologies and provides you high quality data with little to no assay development.
Monolith with MST technology
Monolith comes with MST and enables you to measure high affinity interactions in the pM range, work label-free, or use GFP-tagged proteins