Products & ReviewSeparations

MicroLC and NanoLC Columns

YMC EuropeAvailable: Worldwide

Capillary columns available with every fully porous RP/NP/HILIC phase from YMC for high sensitivity analyses. Compatible with nearly all Nano-/MicroLC/MS systems due to two different connection sizes (1/16" and 1/32").  

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Average Rating 5.0

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Super easy and robust.

 

Average Rating 5.0

Application Area:

Proteomics

Very easy to use, great connections and robustness.

Review Date: 15 Jul 2020 | YMC Europe

YMC offers capillary columns specifically designed for use with the corresponding chromatography systems to meet the requirements of Micro-, Capillary- and NanoLC.

All fully porous RP/NP/HILIC phases from YMC are available in MicroLC and NanoLC columns. They are compatible with nearly all Nano-/MicroLC/MS systems. Capillary columns are suitable for extremely low sample volumes and low flow rates. They are available either with 1/16” connections (10-32 thread) or with 1/32” connections (6-40 thread).

YMC MicroLC and NanoLC Columns Features:

  • All fully porous YMC-phases available
  • Compatible with Micro-/NanoLC/MS systems
  • Extremely low sample volumes and flow rates
  • Guard columns, usable for trapping/desalting
  • Especially designed guard column connector included

YMC MicroLC and NanoLC Columns Characteristics:

  • Phases: RP, NP, HILIC phases
  • Particle Sizes: 1.9, 2, 3 or 5 μm
  • ID: 75, 100, 300, 500 μm
  • Lengths: 50, 75,100, 150 mm
  • Pressure limits: 550 bar for 2, 3 or 5 μm; 600 bar for 1.9 µm

Brochures

Product brochuresLife Sciences

YMC capillary columns for MicroLC and NanoLC

In this brochure, YMC Europe introduces the MicroLC/NanoLC capillary columns specifically designed for rapid high-resolution gradient chromatography, enabling further method optimization and saving both solvent and time. YMC Europe highlights miniaturization of liquid chromatography combined with mass spectrometry for its numerous advantages, such as enhanced sensitivity at low concentration levels and significantly reduced solvent consumption compared to conventional HPLC or UHPLC methods.

Application NoteSeparations

High sensitivity peptide analysis using YMC-Triart C18 UHPLC and MicroLC columns

In this application note, YMC Europe introduces the YMC-Triart C18 UHPLC and MicroLC columns for proteomics analysis. The note emphasizes the necessity of highly sensitive methods in proteomics and native peptidomics analysis due to the wide range of concentrations at which peptides are present in biological samples. The note demonstrates the sensitivity improvement achieved by using UHPLC columns with different internal diameters and a micro-LC approach.


Application NoteSeparations

Veterinary Drug Residues in Food

The levels and presence of veterinary drug residues in food of animal origin are legislated in the EU with limits often varying with the drug residue. The MicroLC method on a YMC-Triart C18 capillary column easily fulfils the requirements of the current EU legislation. The chromatograms clearly demonstrate an improvement in sensitivity when moving to MicroLC. The cut in analysis time provides great potential for cost savings by up to 90% in regards to solvents.


Application NoteSeparations

Gluten in Flour and Cookies

Gluten can cause allergic responses and even celiac disease if an intolerance occurs. The intolerance level is often depending on the gluten variety, which is relevant to the use of oats having low effect on celiac suffers. Here, five different flour samples including a gluten-free and a supermarket self raising flour were analysed for wheat peptide markers. In all the flours except the gluten-free one, wheat peptide markers can be found.

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