In collaboration with key players in the field, Prior Scientific and Life Imaging Services, Nikon Europe has developed LIPSI – a fully incubated, high content screening platform that enables high speed acquisition for up to 20 well plates. Unlike traditional boxed high content systems, Nikon’s LIPSI provides a flexible open platform that can easily evolve to meet changing research needs. Together with our analysis tools, LIPSI enables you to get results from live cells in real time.
LIPSI enables 96-well plate imaging in less than 1.5 min while handling your cells in a fully incubated, temperature controlled, stress-free environment at all stages.
The platform utilises all the functionality of the Eclipse Ti2 inverted microscope, including its 25 mm field of view and capacity for high-speed imaging and can accommodate a wide variety of objectives lenses, fluorescence filters, cameras and other accessories. Use up to two cameras simultaneously for fast multi-colour imaging to increase throughput. Combine fluorescence imaging with brightfield or phase contrast or DIC. Easily upgradable to advanced imaging modalities, such as confocal/ spinning-disk, LIPSI is ready to meet all your current and future research demands.
Nikon’s renowned Perfect Focus System automatically eliminates focus differences between wells or imaging points. Many of our objectives are compatible for glass bottom plates and plastic bottom plates.
Our software includes modules that enable you to image the way you need with just a few clicks. Customize your set ups and analyse your data real time or offline to get the best results without hours of invested training efforts. Some analyses, such as cell count, live/dead, are included inside the software. The General Analysis tool allows you to create the most complex analysis extremely easily. As all the incubator parameters (humidity/CO2/temperature) are registered with every image, it becomes really easy to link the analyses results with the environmental conditions.
The JOBS Viewer gives you results in real time for instant visualization and can also be used on offline workstations to analyse images and visualize results after acquisition. Different tools for data visualization such as bar chart, scatterplot, heatmaps, time charts and line charts are included.