LCMS-8040 Triple Quadrupole Liquid Chromatograph Mass Spectrometer by Shimadzu Corporation

Manufacturer Shimadzu Corporation  |   Model: C146-E188E  |  Available Worldwide
4.3
/
5.0
  |  22 reviews
Consumer demand for higher quality products has led to the implementation of stricter government regulations and oversight in order to ensure safety and product conformity. The food safety community is just one sector requiring lower minimum residue levels with greater testing frequency for a broader number of compounds. The triple quad LCMS-8040 has stepped up to the challenges of high-throughput sensitive routine analysis. As shown, the LCMS-8040 can analyze a 226-pesticide mixture in less tha... Read more


LCMS-8040 Triple Quadrupole Liquid Chromatograph Mass Spectrometer by Shimadzu Corporation product image
LCMS-8040 Triple Quadrupole Liquid Chromatograph Mass Spectrometer
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Average Rating: 4.3
22 Scientists have reviewed this product

4 out of 5
Ease of use
4 out of 5
After sales service
4 out of 5
Value for money


  • Status:

    Advanced Reviewer
  • Member since: 2019

  • Organization: Buckeye Clinic



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Great results.
Rating: 4.3

  • Application Area: Toxicology. Analyze the drugs in the urine.

"The machine has a high quality. The results are always in window. It is easy to use it and after sale the quality is still good."

Review date: 19 Apr 2023 | LCMS-8040 Triple Quadrupole Liquid Chromatograph Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: Eru



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Ease of use, high quality and reproducible results,
Rating: 4.7

  • Application Area:LC MS MS

"Ease of use, high quality and reproducible results,"

Review date: 18 Nov 2022 | LCMS-8040 Triple Quadrupole Liquid Chromatograph Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2022

  • Organization: Food corporation of India



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Great result
Rating: 4.0

  • Application Area:Analysis of pesticide residues & mycotoxins

"The instrument is user-friendly and the service of the dealer is quite good."

Review date: 29 Sep 2022 | LCMS-8040 Triple Quadrupole Liquid Chromatograph Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Amneal injectable



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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This instrument is very precise , sensitive and accurate.
Rating: 5.0

  • Application Area:LCMS

"This instrument is very precise , sensitive and accurate."

Review date: 17 Dec 2021 | LCMS-8040 Triple Quadrupole Liquid Chromatograph Mass Spectrometer
  • Status:

    Advanced Reviewer

  • Member since: 2019

  • Organization: Buckeye Clinic



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Great results, very reliable, a must have for any toxicology lab
Rating: 4.7

  • Application Area:Drug analysis-Toxicology

"Reliable, easy to operate, and reproducible results. Good service with the service contract. Easy to replace guard column and columns. Low breakdown."

Review date: 08 Nov 2021 | LCMS-8040 Triple Quadrupole Liquid Chromatograph Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: eru



  • Ease of use
    5 out of 5
    After sales service
    3 out of 5
    Value for money
    3 out of 5
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Great results but not indispensable.
Rating: 3.7

  • Application Area:Biopharmaceutical/medicinal chemistry

"Shimadzu provides a broad range of analytical instruments indispensable for research, development, and quality control in a variety of fields. High-level, sophisticated instruments include chromatographs, spectrometers, and elemental and surface analysis systems. But they are very expensive. Shimadzu must provide free software for data analysis out of lab or equipment."

Review date: 16 Jul 2021 | LCMS-8040 Triple Quadrupole Liquid Chromatograph Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: Harrens Lab



  • Ease of use
    5 out of 5
    After sales service
    3 out of 5
    Value for money
    4 out of 5
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Great results and very good precision.
Rating: 4.0

  • Application Area:Food, cannabis

"Easy to use for daily testing, Low maintenance. High value."

Review date: 05 May 2021 | LCMS-8040 Triple Quadrupole Liquid Chromatograph Mass Spectrometer
  • Status:

    Advanced Reviewer

  • Member since: 2019

  • Organization: Buckeye Clinic



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great results, can’t live without this instrument!
Rating: 5.0

  • Application Area:Drug analysis

"Ease of operation, Easy maintenance, Reliable results. Good technical support. "

Review date: 02 Feb 2021 | LCMS-8040 Triple Quadrupole Liquid Chromatograph Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: Innovatech



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    3 out of 5
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We look forward to achieving our goals with this instrument.
Rating: 3.7

  • Application Area:Quality control

"We're using it in quality control for services that our laboratory supplies for our customers."

Review date: 08 Dec 2020 | LCMS-8040 Triple Quadrupole Liquid Chromatograph Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: Lipscomb University



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Awesome performance with great value
Rating: 4.7

  • Application Area:Quantitation of drugs in blood plasma

"This instrument was a good value when compared to other vendors when we purchased it. The LabSolutions software is better (or at least easier to use) than some others on the market. The instrument is six years old and is very reliable. Service is also good."

Review date: 06 Mar 2020 | LCMS-8040 Triple Quadrupole Liquid Chromatograph Mass Spectrometer


  • Status:

    Reviewer

  • Member since: 2020

  • Organization: University of Texas at Arlington



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great results - user interface needs some work!
Rating: 4.7

  • Application Area:Extracted amino acids from complex matrices

"The product is extremely effective. The interface is where most people struggle, as it requires a baseline knowledge of tricks and tips from an experienced user to get the best experience. There can be a slight learning curve here. The other issue for chromatographers is the extra column band broadening as the modules for these instruments can require extensive tubing. In general, we have had a lot of success using the instrument with expert help for method development. I would definitely recommend."

Review date: 03 Mar 2020 | LCMS-8040 Triple Quadrupole Liquid Chromatograph Mass Spectrometer
  • Status:

    Expert Reviewer

  • Member since: 2011

  • Organization: INDOCO REMEDIES LTD



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Great instrument for researcher
Rating: 4.3

  • Application Area:Pharmaceutical

"Versatile application, good performance and rugged instrument"

Review date: 11 Jul 2019 | LCMS-8040 Triple Quadrupole Liquid Chromatograph Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: University Of Texas At Arlington



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Easy to operate, robust, sensitive enough for my research purpose.
Rating: 5.0

  • Application Area:Scientific research - analytical chemistry

"Good for quantification of small molecules. Easy to operate, robust, sensitive enough for my research purpose."

Review date: 26 Mar 2019 | LCMS-8040 Triple Quadrupole Liquid Chromatograph Mass Spectrometer
  • Status:

    Expert Reviewer

  • Member since: 2011

  • Organization: INDOCO REMEDIES LTD



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great, simple and nice product.
Rating: 4.7

  • Application Area:Pharmacetical

"The product delivers high quality result compared to other product. The instrument is easy to operate but software somewhat complicated and not advance. We surely would like to recommend this product."

Review date: 15 Mar 2019 | LCMS-8040 Triple Quadrupole Liquid Chromatograph Mass Spectrometer
  • Status:

    Expert Reviewer

  • Member since: 2011

  • Organization: INDOCO REMEDIES LTD



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great sensitivity
Rating: 5.0

  • Application Area:Pharmaceuticals

"A very sensitive and high out put instrument used by the scientist. It finds application in pharmaceuticals for the trace level analysis and impurity profiling. Instrument is rugged and very user friendly."

Review date: 25 Sep 2018 | LCMS-8040 Triple Quadrupole Liquid Chromatograph Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: UMa



  • Ease of use
    3 out of 5
    After sales service
    1 out of 5
    Value for money
    3 out of 5
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It doesn't work more than 2 months without a problem!
Rating: 2.3

  • Application Area:Food chemistry

"In the short time that the equipment worked correctly it was possible to see that it is practical to use, has good sensitivity and is easy to use in general. The problem with this equipment is that it does not work for more than two months without appearing any problem and stop. In two and a half years it doesn't work more than 40 percent of the time. After the warranty period the problems are still accumulating without a guarantee that having enough budget will solve them. This also depends on the representation of the country and, if it is Portugal, I advise you to not buy. The lab's worst acquisition ever."

Review date: 28 May 2018 | LCMS-8040 Triple Quadrupole Liquid Chromatograph Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2004

  • Organization: Firmenich, Inc.



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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A Good Reliable Instrument
Rating: 4.3

  • Application Area:small molecule quantification

"A very sensitive, easy to maintain workhorse triple-quad for low-level quantification of small molecules. Like most software for complex instruments, it takes a while to get used to but it is very powerful and logical. The local technical support team have been great, very responsive and knowledgeable. We have had only one year of experience with this instrument, but it has met our expectations in all but one area. It does not have a heated ESI source, so we have had to modify some methods that were transferred from an instrument that does have a heated source. In the future, I would not purchase an instrument without a heated ESI, which is not available on this model."

Review date: 21 Jul 2017 | LCMS-8040 Triple Quadrupole Liquid Chromatograph Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: Cleveland State University



  • Ease of use
    3 out of 5
    After sales service
    3 out of 5
    Value for money
    4 out of 5
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Great
Rating: 3.3

  • Application Area:Small molecules

"Good more robust if and rugged. Need more sensitivity"

Review date: 08 Mar 2017 | LCMS-8040 Triple Quadrupole Liquid Chromatograph Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Exacte Labs



  • Ease of use
    3 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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System is "working horse" for labs. Reliable ms-system.
Rating: 4.0

  • Application Area:bioequivalence of pharmacy drugs

"This LCMS is reliable and reproducibility for bioequivalence analysis. LC-system one of the best system. But the software is not easy to use. Cheap for a mass-spectrometer."

Review date: 04 Jan 2017 | LCMS-8040 Triple Quadrupole Liquid Chromatograph Mass Spectrometer
  • Status:

    Advanced Reviewer

  • Member since: 2013

  • Organization: National Institute Of Nutrition (nin)



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Great instrument with sensitive data.
Rating: 4.3

  • Application Area:clinical diagnostics

"Shimadzu is a high profile company providing very good instruments. We use LCMS-8040 at our institute and the results are always good. I recommend for it."

Review date: 30 Mar 2016 | LCMS-8040 Triple Quadrupole Liquid Chromatograph Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2015

  • Organization: Federal University of Ouro Preto



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Excellent value for money, very reliable
Rating: 4.7

  • Application Area:Environmental Analysis

"We have been working with Shimadzu LC-IT-TOF mass spectrometry system since 2007. We have acquired a LCMS/MS model 8040 system last year. The mass spectrometer is connected to a Nexera series 30 UHPLC. The performance and reliability is quite impressive. With this instrument we have done several research works at master and PhD. level analysis of emerging contaminants of concern and also routine benzene exposure biomarkers (uSPMA and uTTMA). "

Review date: 24 Nov 2015 | LCMS-8040 Triple Quadrupole Liquid Chromatograph Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2006

  • Organization: Purificacion y Analisis de Fluidos Ltda.



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Rating: 5.0
"Complete LCMSMS solution, this instrument includes a complete method package that speed up the application start-up, a user friendly software and robust HPLC instrument and MSMS detector makes this package the best option for pesticide residual lab and governments lab."

Review date: 24 Sep 2014 | LCMS-8040 Triple Quadrupole Liquid Chromatograph Mass Spectrometer

Consumer demand for higher quality products has led to the implementation of stricter government regulations and oversight in order to ensure safety and product conformity. The food safety community is just one sector requiring lower minimum residue levels with greater testing frequency for a broader number of compounds. The triple quad LCMS-8040 has stepped up to the challenges of high-throughput sensitive routine analysis. As shown, the LCMS-8040 can analyze a 226-pesticide mixture in less than two minutes, making it an ideal instrument for meeting a laboratorys demanding requirements.

Key Features:

  • Ultra-High Sensitivity

By incorporating newly improved ion optics and collision cell technology, the LCMS-8040 provides higher multiple reaction monitoring (MRM) sensitivity. A five-fold increase in sensitivity (reserpine, S/N ratio), as compared with that of LCMS-8030 has been achieved by improving ion focusing and minimizing ion losses between multi-pole lenses. These improvements also yield higher sensitivity for scan mode measurements. This higher sensitivity expands the potential range of LC/MS/MS applications.

  • Ultra-High Speed

The LCMS-8040 was designed to provide significantly higher sensitivity while maintaining the high speed offered by the LCMS-8030. Ultrafast MRM transition speeds, up to 555 MRMs per second, are achieved by Shimadzus UFsweeper collision cell technology, proprietary high-precision quadrupole machining capabilities, and unique high voltage power supply technology. In addition, the LCMS-8040 features the fast polarity switching at 15 msec. With this high-speed performance, the LCMS-8040 can dramatically improve analytical throughput.

  • Ultra-High Reliability

MRM optimization in Shimadzus LCMS systems is based on a rapid series of automated flow injection analyses, requiring only minutes to perform. Multiple compounds can be optimized in an unattended sequence, freeing the analyst from tedious work. MRM parameters optimized for the LCMS-8030 can be transferred to the LCMS-8040, making it possible to transfer methods between systems. The LCMS-8040 offers the same ease of maintenance benefits as the LCMS-8030, and all consumables, such as desolvation lines (DL) and ESI capillaries, are interchangeable as well.

Product Overview

LCMS-8040 Triple Quadrupole Liquid Chromatograph Mass Spectrometer by Shimadzu Corporation product image

LCMS-8040 Triple Quadrupole Liquid Chromatograph Mass Spectrometer

Manufacturer Shimadzu Corporation  |  Available Worldwide

4.3 / 5.0 | 22 reviews