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Status:
Reviewer
Member since: 2018
Organization: UGR
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- Ease of use
- After sales service
- Value for money
Good Chip with reasonable cost:results ratio.
Application Area: Epigenetics
"Infinium® MethylationEPIC BeadChip permits more methylation signals so we have a better picture of epigenetic processes in different NCDs."
Review date: 17 Apr 2018 | Infinium MethylationEPIC Kit
Product Highlights
With the Infinium MethylationEPIC BeadChip Kit, researchers can interrogate over 850,000 methylation sites quantitatively across the genome at single-nucleotide resolution. Multiple samples, including FFPE, can be analyzed in parallel to deliver high-throughput power while minimizing the cost per sample.
Infinium HD array technology enables content selection independent of bias-associated limitations often associated with methylated DNA capture methods. The result is a pan-enhancer and coding region view of the methylome that can be used for epigenome-wide association studies on a variety of human tissues.
Comprehensive Genome-Wide Coverage
This kit includes the following content categories requested by methylation experts:
- CpG sites outside of CpG islands
- Non-CpG methylated sites identified in human stem cells (CHH sites)
- Differentially methylated sites identified in tumor versus normal
- FANTOM5 enhancers
- ENCODE open chromatin and enhancers
- DNase hypersensitive sites
- miRNA promoter regions
- > 90% of content contained on the Illumina HumanMethylation450K BeadChip
