Resolvex® A200 Automated ppSPE Workstation
The Resolvex A200 provides fully automated ppSPE in 1 ml columns and 96-well plates. It uses proven and reliable syringe pump technology to precisely and accurately deliver up to 11 protocol solvents.
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So far easy automated positive pressure device to analyze up to 96 samples.
Analyze proteins in cell and tissue samples
It is a positive-pressure liquid handler and easy to use. It has several connections for buffers, so it is used for washing and eluting. It is suitable for 96 well plates such as S-trap or any filter plates for protein purification. You can easily fetch your protocol and just click run and it will perform the steps. It has different adapters to set your plate position. Also it has range of high and low pressure to push through the liquid.
Review Date: 13 Dec 2023 | Tecan
Clearly recommended for automated SPE proteomics sample cleanup.
SPE proteomics sample preparation
The A200 incredibly improved our throughput and reproducibility in cleaning up peptides before LC-MS analysis. Now it does not matter if we have only a few or 96 samples. It takes the same time and provides the same results. As a facility that is more and more involved in larger clinical and system biology studies, this instrument is essential for success!
Review Date: 13 May 2020 | Tecan
A god send! Saves me hours of manual work trying to process SPE plates.
SPE sample preparation
This is truly a must have instrument for any institution than routinely performs SPE sample preparation. Very versatile instrument for a variety of applications and saves a lot of time and energy.
Review Date: 15 Mar 2019 | Tecan
The Resolvex A200 is designed to provide fully automated positive pressure solid phase extraction (ppSPE), offering hassle-free, walkaway processing in 1 ml columns and 96-well plates. It uses Tecan’s proven and reliable Cavro® syringe pump technology to accurately deliver up to 11 protocol solvents – from deionized water to hexane – via an integrated eight-channel dispensing module.
The system’s gas-based ppSPE technology maximizes reproducibility and processing uniformity across columns and plate wells, with individual channel flow restriction to guarantee robust processing of partly filled plates or column set-ups. It can also be combined with Tecan’s Fluent® or Freedom EVO® liquid handling platforms to create a fully automated workflow.
The Resolvex A200 features an intuitive touchscreen, making it easy to set up and run protocols, as well as ensuring straightforward integration with your laboratory workflows and SOPs. Fully programmable pressure profiles enable optimization of flow rates, helping to reduce processing time and provide reliable analyte recovery. This provides a simple, effective and standardized approach to SPE automation for applications in life sciences research, pharma, food and environmental testing and clinical chemistry.
Brochures
Next-generation positive pressure sample preparation
Explore Tecan's Resolvex® series of equipment for proteomic workflows and automated largescale nucleic acid purification (NAP) processing, of both conventional and large-scale sample volumes. The three instruments, Resolvex® A200, Resolvex® A200 Omics and Resolvex® A200 24, each with independent advantages, provide flexibility to your workbench sample preparation. Applicable to a variety of industries, learn how Resolvex can benefit your analyte clean-up, life sciences research, food and safety testing and environmental monitoring.
Resolvex A200: automated positive pressure processor
Explore the Resolvex® A200, a compact, automated positive pressure processor for precise solid phase extraction (SPE). Programmable dispensing for up to 11 solvents optimizes sample preparation, enhancing accuracy and instrument longevity for labs in clinical, life sciences, food safety, and environmental testing.
Next-generation positive pressure sample preparation with the Resolvex A200
The Resolvex® A200 from Tecan is a compact, standalone system for automated positive pressure solid phase extraction (SPE). Combining programmable dispensing of up to 11 solvents with innovative pressure control, it offers optimized sample preparation with minimal manual intervention. Explore the Resolvex A200 in depth, including its key features such as an automated liquid dispenser, intuitive touchscreen and sensor-controlled movement.
Scalable protein A-based antibody purification with AffinEx columns and Resolvex A200
Monoclonal antibody (mAb) research is driving advancements in targeted therapeutics through cutting-edge protein purification technologies. AffinEx Protein A solid-phase extraction (SPE) columns, paired with Resolvex positive pressure processors, deliver scalable and automatable solutions with superior ambient stability and streamlined workflows. These technologies ensure reliable and efficient IgG recovery. This poster highlights the performance of AffinEx Protein A columns across four formats, showcasing consistent IgG extraction and recovery rates, robust stability under various conditions, and excellent reusability after multiple alkaline cleaning cycles.
Enhance lab efficiency with automated sample prep solutions
Sample extraction and purification are at the core of modern laboratory workflows, supporting vital fields like proteomics, genomics, and biopharmaceutical production. Automation is revolutionizing these processes by reducing human error, increasing throughput, and boosting lab efficiency.
The latest sample prep instruments integrate sample cleanup, evaporation, and resuspension into a single platform, making complex sample prep more efficient and scalable for everything from method development to large-scale purifications.
This eBook provides valuable resources and case studies to guide you through the latest automation technologies. Learn how Tecan’s cutting-edge lab instruments and automated workflow platforms can transform your lab’s efficiency and output.
Explore case studies such as:
- Semi-automated supercoiled plasmid DNA extraction
- Enhanced biomolecule cleanup in mass spectrometry
- Automated high-throughput plasma proteome sample preparation
- Simplified, automated sample preparation
- Automated on-column protein digestion and peptide desalting for high-throughput proteomics
Rapid proteomics sample preparation with on-column digestion
Bottom-up proteomics is widely used for protein identification and post-translational modification analysis. Tecan details the analysis of trypsin-digested bovine serum albumin (BSA) with on-column digestion using its Narrow Bore Extraction™ (NBE) columns, followed by peptide clean up by solid phase extraction (SPE) utilizing Atlas sorbent in the same column. Discover how using the Tecan Resolvex® A200 combined with the on-column digestion capabilities of the NBE columns enables a high throughput and automated method for the digestion and purification of proteolytic peptides.
High-throughput sample prep for extensive plasma proteomics
Plasma proteomics is vital for identifying health and disease biomarkers, but the complexity of plasma samples poses challenges. Tecan describes a scalable and rapid automation platform for preparing plasma samples for proteomic analysis using the ENRICH-iST HT reagent kit, the Fluent® liquid handler, and the Resolvex® A200. The automated ENRICH-iST workflow addresses challenges by enriching low-abundance proteins, facilitating deeper protein identification and quantification compared to manual methods. Tecan highlights the efficiency and robustness of the automated process, showing high-throughput capabilities with minimal user intervention. It demonstrates consistent and reproducible results with over 97% overlap in protein identifications between manual and automated methods, making it a powerful tool for extensive plasma proteome studies.
Kitted universal MAM: Automatable sample processing for all stages of biological drugs
Multiple attribute monitoring (MAM) is an LC-MS based technique designed to simultaneously and directly monitor critical quality attributes (CQAs) of biologics including impurities, PTMs, and sequence. In this poster, Tecan presents an automated solution for the MAM workflow that successfully allows for removal of contaminants through a streamlined workflow usable at all stages from bioreactor to final product.
High throughput silica membrane-based viral RNA extraction using positive pressure
The global COVID-19 pandemic has resulted in a rapid increase in demand for the isolation of viral RNA. In this application note, Tecan outlines a semi-automated extraction workflow for spiked viral RNA and DNA samples using the NucleoSpin 96 Virus kit from MACHEREY-NAGEL on a Resolvex A200 positive pressure workstation. Implementation of a Resolvex A200 positive pressure workstation is shown to reduce hands-on time significantly, allowing 96 samples to be processed in approximately 60 minutes.
Multi-drug extraction from saliva or full blood
In this poster, Tecan scientists detail how they transferred a manual SPE protocol to the automated plate processing and compared different SPE columns for saliva extraction. This poster also describes how Tecan established a fast extraction protocol using SLE plates with post-mortem blood for drug screening of 400 compounds.
Automated proteomics and multiomics sample preparation
In this poster, learn how the Resolvex® A200 automated ppSPE workstation and the S-Trap™ 96-well plate can increase both throughput and robustness of automated sample preparation for clinical applications of proteomics.
A novel protein digestion workflow for the analysis of surrogate peptides by LC-MS/MS
In this poster, Tecan presents a novel protein digestion workflow to increase the efficiency of the pellet digestion protocol using Control Flow Plate (CFP), Narrow Bore Extraction Plate (NBEP), and the SMART Digest Kit. The poster highlights a specially designed Flow Control Tube format which promises to eliminate centrifugation steps and allows the protein denaturation and digestion steps to be performed in a single tube.
Automated SPE of drugs and their metabolites
In this application note, Tecan discusses the results of performing solid phase extraction (SPE) on oral fluid samples and suggests a potential need for individual protocols for optimized data collection.
Automated proteomics and multi-omics sample preparation
In this video walkthrough, discover an automated, high-throughput positive pressure solid-phase extraction (ppSPE) system that's designed to bring simplicity and reproducibility to proteomics workflows. Combining programmable dispensing of up to
11 solvents with innovative pressure control, it offers optimized sample preparation with minimal manual intervention.
Resolvex<sup>®</sup> A200: Automated positive pressure processor
The Resolvex A200 is a compact standalone system for automated positive pressure solid phase extraction (SPE). Combining programmable dispensing of up to 11 solvents with innovative pressure control, it offers optimized sample preparation with minimal manual intervention. Implementation of positive pressure workflows leads to cleaner SPE samples, improving accuracy, precision and method robustness, as well as extending the lifetime of your analytical instrument.
The need for high-throughput sample preparation in proteomics
Discover how the Resolvex A200 streamlines solid phase extraction (SPE) for proteomics with precise positive pressure technology, high-throughput automation, and reproducible results
Boost workflow efficiency and flexibility with the next generation of Resolvex A200 positive pressure processors
These automated solutions have been designed to offer time savings and improved throughput whilst still providing great reproducibility and robustness
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Automated proteomics sample prep: Realizing the need for higher throughput, robustness & standardization
Watch this on-demand webinar to find out how to quickly and easily prepare samples for proteomics analysis without further method development
New resources to advance your COVID-19 research
Discover the latest technologies and techniques to aid research into the biology, detection, and prevention of SARS-CoV-2 infection
Tecan and ProtiFi announce collaborative partnership for integrated proteomics
The combined solution aims to enable researchers to reproducibly prepare samples of all types for mass spectrometry-based proteomics
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From cannabis testing to environmental monitoring, find out how scientists are using SPE to speed up and innovate their sample preparation
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Discover a range of new technologies and applications for biopharmaceutical development in this special editorial feature
