Scalable protein A-based antibody purification with AffinEx columns and Resolvex A200

18 Nov 2024

Monoclonal antibody (mAb) research is driving advancements in targeted therapeutics through cutting-edge protein purification technologies. AffinEx Protein A solid-phase extraction (SPE) columns, paired with Resolvex positive pressure processors, deliver scalable and automatable solutions with superior ambient stability and streamlined workflows. These technologies ensure reliable and efficient IgG recovery. This poster highlights the performance of AffinEx Protein A columns across four formats, showcasing consistent IgG extraction and recovery rates, robust stability under various conditions, and excellent reusability after multiple alkaline cleaning cycles.

AffinEx™ Protein A

Tecan

AffinEx™ Protein A is a dry-state protein purification device offered in Tecan's unique Narrow Bore Extraction™ (NBE™) format. Protein A binds to the Fc-region of monoclonal antibodies while the NBE format provides increased interactions between the target analyte and sorbent bed.

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Resolvex® A200 Automated ppSPE Workstation

Tecan

The Resolvex A200 provides fully automated ppSPE in 1 ml columns and 96-well plates. It uses proven and reliable syringe pump technology to precisely and accurately deliver up to 11 protocol solvents.

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