AffinEx™ Protein A
AffinEx™ Protein A is a dry-state protein purification device offered in Tecan's unique Narrow Bore Extraction™ (NBE™) format. Protein A binds to the Fc-region of monoclonal antibodies while the NBE format provides increased interactions between the target analyte and sorbent bed.
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AffinEx™ Protein A is a protein A-bound, rigid polymeric sorbent with a polymethylmethacrylate (PMMA) matrix to provide structural stability when dry saving costs during shipping and handling. Designed for antibody purification from various cell culture samples, AffinEx's unique matrix removes the need for cold/wet storage and provides a shelf life of 24 months in ambient conditions without losing extraction efficacy. The unique NBE format storing AffinEx provides opportunities for increased interactions and in-column reactions with automation capabilities optimized for Tecan's Resolvex positive pressure processors.
Brochures
Antibody purification for critical attributes and process development
Tecan highlights AffinEx™ Protein A Capture, as a solution for antibody purification, featuring a protein A-bound rigid polymeric sorbent with a polymethylmethacrylate (PMMA) matrix for structural stability during shipping and handling. Its unique design eliminates the need for cold/wet storage and provides a shelf life of 24 months in ambient conditions without compromising extraction efficacy. Available in Narrow Bore Extraction™ (NBE™) format, it facilitates automated workflows compatible with existing instruments like Resolvex® positive pressure processors. AffinEx's automation-friendly design, extended shelf life, and upcoming expansion to Cerex® columns make it a cost-effective and efficient solution for antibody purification across various scales.
Scalable protein A-based antibody purification with AffinEx columns and Resolvex A200
Monoclonal antibody (mAb) research is driving advancements in targeted therapeutics through cutting-edge protein purification technologies. AffinEx Protein A solid-phase extraction (SPE) columns, paired with Resolvex positive pressure processors, deliver scalable and automatable solutions with superior ambient stability and streamlined workflows. These technologies ensure reliable and efficient IgG recovery. This poster highlights the performance of AffinEx Protein A columns across four formats, showcasing consistent IgG extraction and recovery rates, robust stability under various conditions, and excellent reusability after multiple alkaline cleaning cycles.
Enhance lab efficiency with automated sample prep solutions
Sample extraction and purification are at the core of modern laboratory workflows, supporting vital fields like proteomics, genomics, and biopharmaceutical production. Automation is revolutionizing these processes by reducing human error, increasing throughput, and boosting lab efficiency.
The latest sample prep instruments integrate sample cleanup, evaporation, and resuspension into a single platform, making complex sample prep more efficient and scalable for everything from method development to large-scale purifications.
This eBook provides valuable resources and case studies to guide you through the latest automation technologies. Learn how Tecan’s cutting-edge lab instruments and automated workflow platforms can transform your lab’s efficiency and output.
Explore case studies such as:
- Semi-automated supercoiled plasmid DNA extraction
- Enhanced biomolecule cleanup in mass spectrometry
- Automated high-throughput plasma proteome sample preparation
- Simplified, automated sample preparation
- Automated on-column protein digestion and peptide desalting for high-throughput proteomics
The need for high-throughput sample preparation in proteomics
Discover how the Resolvex A200 streamlines solid phase extraction (SPE) for proteomics with precise positive pressure technology, high-throughput automation, and reproducible results
